(±)-4-O-allyl-1-O-benzyl-2,3;5,6-di-O-isopropylidene-myo-inositol

Base Information

• Chemical Name: (±)-4-O-allyl-1-O-benzyl-2,3;5,6-di-O-isopropylidene-myo-inositol
• CAS No.: 131146-87-7
• Molecular Formula: C₂₂H₃₀O₆
• Molecular Weight: 390.477
• Mol file: 131146-87-7.mol

Synonyms:(±)-4-O-allyl-1-O-benzyl-2,3;5,6-di-O-isopropylidene-myo-inositol

Chemical Property of (±)-4-O-allyl-1-O-benzyl-2,3;5,6-di-O-isopropylidene-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (±)-4-O-allyl-1-O-benzyl-2,3;5,6-di-O-isopropylidene-myo-inositol

There total 16 articles about (±)-4-O-allyl-1-O-benzyl-2,3;5,6-di-O-isopropylidene-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl chloride (100-44-7) + (±)-1-O-allyl-2,3:5,6-di-O-isopropylidene-myo-inositol (111392-28-0,111466-17-2) → (±)-1-O-allyl-4-O-benzyl-2,3:5,6-di-O-isopropylidene-myo-inositol (131146-87-7)

Guidance literature:

With sodium hydride;

DOI:10.1039/c39930001687

Reference yield: 99.0%

benzyl bromide (100-39-0) + (±)-1-O-allyl-2,3:5,6-di-O-isopropylidene-myo-inositol (111392-28-0,111466-17-2) → (±)-1-O-allyl-4-O-benzyl-2,3:5,6-di-O-isopropylidene-myo-inositol (131146-87-7)

Guidance literature:

(±)-1-O-allyl-2,3:5,6-di-O-isopropylidene-myo-inositol; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h; Inert atmosphere;

benzyl bromide; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.ejmech.2015.01.064

Reference yield: 99.0%

(±)-3-O-benzyl-1,2:4,5-di-O-isopropylidene-myo-inositol (58706-24-4,58769-25-8,98974-91-5,111466-16-1) + allyl bromide (106-95-6) → (±)-4-O-allyl-1-O-benzyl-2,3;5,6-di-O-isopropylidene-myo-inositol (131146-87-7)

Guidance literature:

(±)-3-O-benzyl-1,2:4,5-di-O-isopropylidene-myo-inositol; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h; Inert atmosphere;

allyl bromide; With sodium iodide; In N,N-dimethyl-formamide; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.ejmech.2015.01.064

upstream raw materials:

(±)-3-O-benzyl-1,2:4,5-di-O-isopropylidene-myo-inositol

(+/-)-1,2:4,5-di-O-isopropylidene-6-O-p-methoxybenzyl-myo-inositol

allyl bromide

(+/-)-1,2:4,5-di-O-isopropylidene-myo-inositol

Downstream raw materials:

(+)-1-O-allyl-4,5,6-tri-O-benzyl-1D-myo-inositol

(-)-3-O-allyl-4,5,6-tri-O-benzyl-1D-myo-inositol