benzyl [(2R)-2-{4-(benzyloxy)-3-[(methylsulfonyl)amino]phenyl}-2-hydroxyethyl][2-(4-bromophenyl)ethyl]carbamate

Base Information

• Chemical Name: benzyl [(2R)-2-{4-(benzyloxy)-3-[(methylsulfonyl)amino]phenyl}-2-hydroxyethyl][2-(4-bromophenyl)ethyl]carbamate
• CAS No.: 855482-76-7
• Molecular Formula: C₃₂H₃₃BrN₂O₆S
• Molecular Weight: 653.594

Synonyms:benzyl [(2R)-2-{4-(benzyloxy)-3-[(methylsulfonyl)amino]phenyl}-2-hydroxyethyl][2-(4-bromophenyl)ethyl]carbamate

Chemical Property of benzyl [(2R)-2-{4-(benzyloxy)-3-[(methylsulfonyl)amino]phenyl}-2-hydroxyethyl][2-(4-bromophenyl)ethyl]carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl [(2R)-2-{4-(benzyloxy)-3-[(methylsulfonyl)amino]phenyl}-2-hydroxyethyl][2-(4-bromophenyl)ethyl]carbamate

There total 1 articles about benzyl [(2R)-2-{4-(benzyloxy)-3-[(methylsulfonyl)amino]phenyl}-2-hydroxyethyl][2-(4-bromophenyl)ethyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.6%

C31H31BrN2O4 + methanesulfonyl chloride (124-63-0) → benzyl [(2R)-2-{4-(benzyloxy)-3-[(methylsulfonyl)amino]phenyl}-2-hydroxyethyl][2-(4-bromophenyl)ethyl]carbamate (855482-76-7)

Guidance literature:

With pyridine; at 20 ℃; for 4.5h;

DOI:10.1021/jm8000345

Reference yield:

[3-isopropoxy-4-[(N-methanesulfonyl)carbamoyl]phenyl]boronic acid + benzyl [(2R)-2-{4-(benzyloxy)-3-[(methylsulfonyl)amino]phenyl}-2-hydroxyethyl][2-(4-bromophenyl)ethyl]carbamate (855482-76-7) → C43H47N3O10S2

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; at 20 - 75 ℃; for 10h;

Reference yield:

benzyl [(2R)-2-{4-(benzyloxy)-3-[(methylsulfonyl)amino]phenyl}-2-hydroxyethyl][2-(4-bromophenyl)ethyl]carbamate (855482-76-7) + 3-isopropoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid (1038595-55-9) → C42H44N2O9S

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; water; at 70 ℃; for 10h; Inert atmosphere;

DOI:10.1021/jm8000345

upstream raw materials:

methanesulfonyl chloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 855482-76-7 benzyl [(2R)-2-{4-(benzyloxy)-3-[(methylsulfonyl)amino]phenyl}-2-hydroxyethyl][2-(4-bromophenyl)ethyl]carbamate

Send

Send

Metric Ton KG G Pound L ML

Send

Send