N-<2-(3,4-dimethoxyphenyl)ethyl>-N-methyl-1,5-pentanediamine

Base Information

• Chemical Name: N-<2-(3,4-dimethoxyphenyl)ethyl>-N-methyl-1,5-pentanediamine
• CAS No.: 101725-28-4
• Molecular Formula: C₁₆H₂₈N₂O₂
• Molecular Weight: 280.411
• Mol file: 101725-28-4.mol

Synonyms:N-<2-(3,4-dimethoxyphenyl)ethyl>-N-methyl-1,5-pentanediamine

Chemical Property of N-<2-(3,4-dimethoxyphenyl)ethyl>-N-methyl-1,5-pentanediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<2-(3,4-dimethoxyphenyl)ethyl>-N-methyl-1,5-pentanediamine

There total 8 articles about N-<2-(3,4-dimethoxyphenyl)ethyl>-N-methyl-1,5-pentanediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]pentanenitrile (101438-79-3) → N-<2-(3,4-dimethoxyphenyl)ethyl>-N-methyl-1,5-pentanediamine (101725-28-4)

Guidance literature:

With sodium hydroxide; hydrogen; nickel; In ethanol; for 12h; under 2068.59 Torr;

DOI:10.1016/j.bmc.2006.07.055

Reference yield: 55.0%

N-methylhomoveratrylamine (3490-06-0) + 4-bromovalero-nitrile (14470-12-3) → N-<2-(3,4-dimethoxyphenyl)ethyl>-N-methyl-1,5-pentanediamine (101725-28-4)

Guidance literature:

With hydrogenchloride; ammonia; potassium carbonate; In ethanol; water; N,N-dimethyl-formamide;

Reference yield:

N-methylhomoveratrylamine (3490-06-0) → N-<2-(3,4-dimethoxyphenyl)ethyl>-N-methyl-1,5-pentanediamine (101725-28-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / sodium carbonate; sodium iodide / 2-methyl-propan-2-ol / 24 h / Heating

2: 80 percent / NaOH; hydrogen; nickel / ethanol / 12 h / 2068.59 Torr

With sodium hydroxide; hydrogen; nickel; sodium carbonate; sodium iodide; In ethanol; tert-butyl alcohol;

DOI:10.1016/j.bmc.2006.07.055

upstream raw materials:

5-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]pentanenitrile

N-methylhomoveratrylamine

δ-chlorovaleronitrile

5-bromopentan-1-nitrile

Downstream raw materials:

2-amino-N-{5-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]pentyl}benzamide