1,1,1,3,3,3-hexafluoro-2-[2-(3,3,3-trifluoro-1-phenyl-2-phenylamino-2-trifluoromethyl-propylselanyl)-phenyl]-propan-2-ol

Base Information

• Chemical Name: 1,1,1,3,3,3-hexafluoro-2-[2-(3,3,3-trifluoro-1-phenyl-2-phenylamino-2-trifluoromethyl-propylselanyl)-phenyl]-propan-2-ol
• CAS No.: 334866-56-7
• Molecular Formula: C₂₅H₁₇F₁₂NOSe
• Molecular Weight: 654.357
• Mol file: 334866-56-7.mol

Synonyms:1,1,1,3,3,3-hexafluoro-2-[2-(3,3,3-trifluoro-1-phenyl-2-phenylamino-2-trifluoromethyl-propylselanyl)-phenyl]-propan-2-ol

Chemical Property of 1,1,1,3,3,3-hexafluoro-2-[2-(3,3,3-trifluoro-1-phenyl-2-phenylamino-2-trifluoromethyl-propylselanyl)-phenyl]-propan-2-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1,1,3,3,3-hexafluoro-2-[2-(3,3,3-trifluoro-1-phenyl-2-phenylamino-2-trifluoromethyl-propylselanyl)-phenyl]-propan-2-ol

There total 1 articles about 1,1,1,3,3,3-hexafluoro-2-[2-(3,3,3-trifluoro-1-phenyl-2-phenylamino-2-trifluoromethyl-propylselanyl)-phenyl]-propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[1-({2-[1-(tert-butyl-dimethyl-silanyloxy)-2,2,2-trifluoro-1-trifluoromethyl-ethyl]-phenylselanyl}-phenyl-methyl)-2,2,2-trifluoro-1-trifluoromethyl-ethyl]-phenyl-amine (334866-55-6) → 1,1,1,3,3,3-hexafluoro-2-[2-(3,3,3-trifluoro-1-phenyl-2-phenylamino-2-trifluoromethyl-propylselanyl)-phenyl]-propan-2-ol (334866-56-7)

Guidance literature:

With tetrabutyl ammonium fluoride;

DOI:10.1080/10426500108546564

Reference yield: 40.0%

1,1,1,3,3,3-hexafluoro-2-[2-(3,3,3-trifluoro-1-phenyl-2-phenylamino-2-trifluoromethyl-propylselanyl)-phenyl]-propan-2-ol (334866-56-7) → trans-4'-phenyl-3,3,3',3'-tetrakis(trifluoromethyl)-3H-spiro[[2.1]benzoxaselenole-1<*>14,1'-[1.2]-selenazetidine] + C6H4SeCH2C6H5C(CF3)2OC(CF3)2NHC6H3

Guidance literature:

With chloroform; 3-chloro-benzenecarboperoxoic acid; at 0 ℃; for 0.5h;

DOI:10.1021/ol007015m

Reference yield:

1,1,1,3,3,3-hexafluoro-2-[2-(3,3,3-trifluoro-1-phenyl-2-phenylamino-2-trifluoromethyl-propylselanyl)-phenyl]-propan-2-ol (334866-56-7) → benzaldehyde (100-52-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 40 percent / mCPBA; CHCl₃ / 0.5 h / 0 °C

2: 16 percent Spectr_. / various solvent(s) / 210 °C

With chloroform; 3-chloro-benzenecarboperoxoic acid; In various solvent(s);

DOI:10.1021/ol007015m

upstream raw materials:

[1-({2-[1-(tert-butyl-dimethyl-silanyloxy)-2,2,2-trifluoro-1-trifluoromethyl-ethyl]-phenylselanyl}-phenyl-methyl)-2,2,2-trifluoro-1-trifluoromethyl-ethyl]-phenyl-amine

Downstream raw materials:

N-(1,1,1,3,3,3-hexafluoropropyl)aniline

benzaldehyde