tert-butyl 1-(4-bromo-2-fluorobenzyl)-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

Base Information

Chemical Name:tert-butyl 1-(4-bromo-2-fluorobenzyl)-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate
CAS No.:1426689-05-5
Molecular Formula:C₂₃H₂₄BrFN₂O₃
Molecular Weight:475.358
Hs Code.:

Synonyms:tert-butyl 1-(4-bromo-2-fluorobenzyl)-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

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Chemical Property of tert-butyl 1-(4-bromo-2-fluorobenzyl)-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

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Technology Process of tert-butyl 1-(4-bromo-2-fluorobenzyl)-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

There total 1 articles about tert-butyl 1-(4-bromo-2-fluorobenzyl)-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76283-09-5
4-bromo-2-fluorobenzyl bromide

: 205383-87-5
tert-butyl 2-oxospiro[indoline-3,3’-pyrrolidine]-1'-carboxylate

: 1426689-05-5
tert-butyl 1-(4-bromo-2-fluorobenzyl)-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

Guidance literature:: With potassium carbonate; In acetonitrile;
DOI:10.1016/j.bmcl.2013.01.017

Reference yield:

: 1426689-05-5
tert-butyl 1-(4-bromo-2-fluorobenzyl)-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

: 761446-44-0
1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

: 1426688-88-1
C₂₇H₂₉FN₄O₃

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; caesium carbonate; In tetrahydrofuran; water; at 160 ℃; for 0.166667h; Microwave irradiation; Sealed tube;

Reference yield:

: 1426689-05-5
tert-butyl 1-(4-bromo-2-fluorobenzyl)-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

: 1426689-19-1
C₂₉H₃₃FN₄O₃

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; caesium carbonate; In tetrahydrofuran; water; at 160 ℃; for 0.166667h;
DOI:10.1016/j.bmcl.2013.01.017