2-[phenyl(2-benzoyloxyethyl)amino]ethyl benzoate

Base Information

• Chemical Name: 2-[phenyl(2-benzoyloxyethyl)amino]ethyl benzoate
• CAS No.: 24867-51-4
• Molecular Formula: C₂₄H₂₃NO₄
• Molecular Weight: 389.451
• Mol file: 24867-51-4.mol

Synonyms:2-[phenyl(2-benzoyloxyethyl)amino]ethyl benzoate

Chemical Property of 2-[phenyl(2-benzoyloxyethyl)amino]ethyl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[phenyl(2-benzoyloxyethyl)amino]ethyl benzoate

There total 1 articles about 2-[phenyl(2-benzoyloxyethyl)amino]ethyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2,2'-(phenylimino)bis[ethanol] (120-07-0) + benzoyl chloride (98-88-4) → 2-[phenyl(2-benzoyloxyethyl)amino]ethyl benzoate (24867-51-4)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1039/a904598h

Reference yield: 78.0%

2-[phenyl(2-benzoyloxyethyl)amino]ethyl benzoate (24867-51-4) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 2-[(4-formylphenyl)(2-benzoyloxyethyl)amino]ethyl benzoate (65072-25-5)

Guidance literature:

With trichlorophosphate; at 80 ℃; for 3h;

DOI:10.1039/a902230i

Reference yield:

2-[phenyl(2-benzoyloxyethyl)amino]ethyl benzoate (24867-51-4) → 4-[bis(2-hydroxyethyl)amino]-4'-nitrostilbene (117563-47-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 78 percent / POCl₃ / 3 h / 80 °C

2: NaH / tetrahydrofuran / 16 h / 70 °C

3: NaOH / methanol / 12 h / 80 °C

With sodium hydroxide; sodium hydride; trichlorophosphate; In tetrahydrofuran; methanol; 1: Formylation / 2: Horner-Emmons-Wittig reaction / 3: Hydrolysis;

DOI:10.1039/a902230i

upstream raw materials:

2,2'-(phenylimino)bis[ethanol]

benzoyl chloride

Downstream raw materials:

2-[(4-formylphenyl)(2-benzoyloxyethyl)amino]ethyl benzoate

4-[bis(2-hydroxyethyl)amino]-4'-nitrostilbene

4-{bis[2-(4-nitrophthalimido)ethyl]amino}-4'-nitrostilbene

Refernces

• 1、 Yoon, Chong-Bok,Shim, Hong-Ku. "Facile synthesis of new NLO-functionalized polyimides via Mitsunobu reaction". . p. 2339 - 2344. Retrieved 1999.