Technology Process of 2-(2,4-dimethylphenyl)-3-vinylisoindolin-1-one
There total 6 articles about 2-(2,4-dimethylphenyl)-3-vinylisoindolin-1-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
1,10-Phenanthroline; oxygen; palladium diacetate;
In
methanol;
at 60 ℃;
for 12h;
under 760.051 Torr;
regioselective reaction;
Cooling with liquid nitrogen;
DOI:10.1021/ol203043h
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium tert-butylate / tetrahydrofuran / 2.16 h / 0 - 20 °C / Inert atmosphere
1.2: 24 h / 0 - 20 °C / Inert atmosphere
2.1: thionyl chloride / dichloromethane; N,N-dimethyl-formamide / 5 h / Reflux; Inert atmosphere
3.1: dichloromethane / 0.08 h / 0 °C / Inert atmosphere
3.2: 12 h / 0 - 20 °C / Inert atmosphere
4.1: 1,10-Phenanthroline; oxygen; palladium diacetate / methanol / 12 h / 60 °C / 760.05 Torr / Cooling with liquid nitrogen
With
thionyl chloride; 1,10-Phenanthroline; potassium tert-butylate; oxygen; palladium diacetate;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol203043h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: thionyl chloride / dichloromethane; N,N-dimethyl-formamide / 5 h / Reflux; Inert atmosphere
2.1: dichloromethane / 0.08 h / 0 °C / Inert atmosphere
2.2: 12 h / 0 - 20 °C / Inert atmosphere
3.1: 1,10-Phenanthroline; oxygen; palladium diacetate / methanol / 12 h / 60 °C / 760.05 Torr / Cooling with liquid nitrogen
With
thionyl chloride; 1,10-Phenanthroline; oxygen; palladium diacetate;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol203043h
