C₂₈H₃₀N₂O₄

Base Information

• Chemical Name: C₂₈H₃₀N₂O₄
• CAS No.: 1320267-36-4
• Molecular Formula: C₂₈H₃₀N₂O₄
• Molecular Weight: 458.557
• Mol file: 1320267-36-4.mol

Synonyms:C₂₈H₃₀N₂O₄

Chemical Property of C₂₈H₃₀N₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₃₀N₂O₄

There total 1 articles about C₂₈H₃₀N₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

Propargylic aldehyde (624-67-9) + C26H32N2O3Se → C28H30N2O4 (1320267-36-4)

Guidance literature:

With tribromoacetic acid; C₁₉H₂₄N₂O; In toluene; at -40 - 23 ℃; optical yield given as %ee; enantioselective reaction;

DOI:10.1038/nature10232

Reference yield: 76.0%

phosgene (75-44-5) + (Z)-4-bromo-3-iodobut-2-en-1-yl acetate (1320267-38-6) + C28H30N2O4 (1320267-36-4) → C27H31IN2O3 (1320267-40-0)

Guidance literature:

C₂₈H₃₀N₂O₄; With Wilkinson's catalyst; benzonitrile; In toluene; at 120 ℃;

phosgene; With triethylamine; In toluene; at -45 - 23 ℃;

(Z)-4-bromo-3-iodobut-2-en-1-yl acetate; Further stages;

DOI:10.1038/nature10232

Reference yield:

C28H30N2O4 (1320267-36-4) → strychnidin-10-one (57-24-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: Wilkinson's catalyst; benzonitrile / toluene / 120 °C

1.2: -45 - 23 °C

2.1: tetrabutyl-ammonium chloride; palladium diacetate; sodium hydrogencarbonate / ethyl acetate / 23 °C

3.1: thiophenol; trifluoroacetic acid / 45 °C

4.1: sodium acetate; acetic anhydride / acetic acid / 120 °C

With Wilkinson's catalyst; tetrabutyl-ammonium chloride; sodium acetate; palladium diacetate; acetic anhydride; sodium hydrogencarbonate; thiophenol; benzonitrile; trifluoroacetic acid; In acetic acid; ethyl acetate; toluene; 2.1: Heck reaction;

DOI:10.1038/nature10232

upstream raw materials:

Propargylic aldehyde

Downstream raw materials:

C₂₇H₃₀N₂O₃

strychnidin-10-one

C₂₄H₂₆N₂O₃

C₂₇H₃₁IN₂O₃

Refernces