2-(4-hydroxy-2,3,5-trimethylbenzoyl)-3,6-dimethylbenzoic acid

Base Information

• Chemical Name: 2-(4-hydroxy-2,3,5-trimethylbenzoyl)-3,6-dimethylbenzoic acid
• CAS No.: 198777-87-6
• Molecular Formula: C₁₉H₂₀O₄
• Molecular Weight: 312.365
• Mol file: 198777-87-6.mol

Synonyms:2-(4-hydroxy-2,3,5-trimethylbenzoyl)-3,6-dimethylbenzoic acid

Chemical Property of 2-(4-hydroxy-2,3,5-trimethylbenzoyl)-3,6-dimethylbenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-(4-hydroxy-2,3,5-trimethylbenzoyl)-3,6-dimethylbenzoic acid

There total 1 articles about 2-(4-hydroxy-2,3,5-trimethylbenzoyl)-3,6-dimethylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

3,6-dimethyl phthalic anhydride (5463-50-3) + 2,3,6-trimethylphenol (2416-94-6) → 2-(4-hydroxy-2,3,5-trimethylbenzoyl)-3,6-dimethylbenzoic acid (198777-87-6)

Guidance literature:

With aluminium trichloride; In 1,2-dichloro-benzene; at 70 ℃; for 24h;

DOI:10.1002/prac.199733901115

Reference yield: 53.0%

2-(4-hydroxy-2,3,5-trimethylbenzoyl)-3,6-dimethylbenzoic acid (198777-87-6) → 2-(4-hydroxy-2,3,5-trimethylbenzyl)-3,6-dimethylbenzoic acid (198777-91-2)

Guidance literature:

With hydrogenchloride; mercury; zinc; In acetic acid; for 1.5h; Heating;

DOI:10.1002/prac.199733901115

Reference yield: 42.0%

2-(4-hydroxy-2,3,5-trimethylbenzoyl)-3,6-dimethylbenzoic acid (198777-87-6) → 3-(4-hydroxy-2,3,5-trimethylphenyl)-4,7-dimethyl-1,3-dihydro-1-isobenzofuranone

Guidance literature:

With hydrogenchloride; mercury; zinc; In acetic acid; for 2h; Heating;

DOI:10.1002/prac.199733901115

upstream raw materials:

3,6-dimethyl phthalic anhydride

2,3,6-trimethylphenol

Downstream raw materials:

2-(4-hydroxy-2,3,5-trimethylbenzyl)-3,6-dimethylbenzoic acid