4-(2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

Base Information

Chemical Name:4-(2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline
CAS No.:1123838-11-8
Molecular Formula:C₂₂H₁₈FN₃O₃S
Molecular Weight:423.468
Hs Code.:

Synonyms:4-(2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

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Chemical Property of 4-(2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

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Technology Process of 4-(2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

There total 5 articles about 4-(2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1123838-08-3
2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine

: 1123838-11-8
4-(2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

Guidance literature:: With iron; ammonium chloride; In ethanol; water; for 0.5h; Product distribution / selectivity; Heating / reflux;

Reference yield: 88.0%

: 1123838-05-0
2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)-7-chlorothieno[3,2-b]pyridine

: 399-96-2
4-amino-2-fluorophenol

: 1123838-11-8
4-(2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

Guidance literature:: 4-amino-2-fluorophenol; With potassium tert-butylate; In dimethyl sulfoxide; for 0.5h;

2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)-7-chlorothieno[3,2-b]pyridine; In dimethyl sulfoxide; at 100 ℃; for 1.5h;

Reference yield: 88.0%

: 2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)-7-chlorothieno[3,2-d]pyridine

: 399-96-2
4-amino-2-fluorophenol

: 1123838-11-8
4-(2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

Guidance literature:: 4-amino-2-fluorophenol; With potassium tert-butylate; In dimethyl sulfoxide; for 0.5h;

2-(5-(1,3-dioxan-2-yl)pyridin-2-yl)-7-chlorothieno[3,2-d]pyridine; In dimethyl sulfoxide; at 100 ℃; for 1.5h; Product distribution / selectivity;