1-acetoxy-1-phenyl-2-isopropylthioethane

Base Information

• Chemical Name: 1-acetoxy-1-phenyl-2-isopropylthioethane
• CAS No.: 121045-17-8
• Molecular Formula: C₁₃H₁₈O₂S
• Molecular Weight: 238.351
• Mol file: 121045-17-8.mol

Synonyms:1-acetoxy-1-phenyl-2-isopropylthioethane

Chemical Property of 1-acetoxy-1-phenyl-2-isopropylthioethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-acetoxy-1-phenyl-2-isopropylthioethane

There total 4 articles about 1-acetoxy-1-phenyl-2-isopropylthioethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

acetic anhydride (108-24-7) + 2-(isopropylthio)-1-phenylethan-1-ol (121045-46-3) → 1-acetoxy-1-phenyl-2-isopropylthioethane (121045-17-8)

Guidance literature:

With pyridine; In dichloromethane; for 20h; Ambient temperature;

Reference yield: 80.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + diisopropyl sulfide (4253-89-8) + acetic acid (64-19-7,77671-22-8) → 1-acetoxy-1-phenyl-2-isopropylthioethane (121045-17-8)

Guidance literature:

With [2,2]bipyridinyl; copper(l) iodide; oxygen; In N,N-dimethyl-formamide; at 90 ℃; for 36h;

DOI:10.1021/jo060834l

Reference yield:

2-isopropylsulfanyl-1-phenyl-ethanone (66502-11-2) → 1-acetoxy-1-phenyl-2-isopropylthioethane (121045-17-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / NaBH₄ / methanol / 6 h / Ambient temperature

2: 84 percent / pyridine / CH₂Cl₂ / 20 h / Ambient temperature

With pyridine; sodium tetrahydroborate; In methanol; dichloromethane;

upstream raw materials:

acetic anhydride

2-(isopropylthio)-1-phenylethan-1-ol

styrene

diisopropyl sulfide

Downstream raw materials:

ethyl 2,3-dihydro-3-isopropylthio-2-phenyl-1-benzofuran-5-carboxylate

2-methoxyethyl 2-phenyl-1-benzofuran-5-carboxylate

5-methyl-2-phenylbenzofuran

2-phenyl-1-benzofuran-5-carbaldehyde