diethyl 2-(3,4-dimethoxybenzylidene)-3-(3,4-methylenedioxybenzyl)succinate

Base Information

Chemical Name:diethyl 2-(3,4-dimethoxybenzylidene)-3-(3,4-methylenedioxybenzyl)succinate
CAS No.:1220632-88-1
Molecular Formula:C₂₅H₂₈O₈
Molecular Weight:456.493
Hs Code.:

Synonyms:diethyl 2-(3,4-dimethoxybenzylidene)-3-(3,4-methylenedioxybenzyl)succinate

Suppliers and Price of diethyl 2-(3,4-dimethoxybenzylidene)-3-(3,4-methylenedioxybenzyl)succinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of diethyl 2-(3,4-dimethoxybenzylidene)-3-(3,4-methylenedioxybenzyl)succinate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of diethyl 2-(3,4-dimethoxybenzylidene)-3-(3,4-methylenedioxybenzyl)succinate

There total 2 articles about diethyl 2-(3,4-dimethoxybenzylidene)-3-(3,4-methylenedioxybenzyl)succinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 2606-51-1
3,4-Methylenedioxybenzyl bromide

: 289622-16-8
diethyl 2-(3,4-dimethoxybenzylidene)succinate

: 1220632-88-1
diethyl 2-(3,4-dimethoxybenzylidene)-3-(3,4-methylenedioxybenzyl)succinate

Guidance literature:: diethyl 2-(3,4-dimethoxybenzylidene)succinate; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.333333h; Inert atmosphere;

3,4-Methylenedioxybenzyl bromide; In tetrahydrofuran; at -78 ℃; for 2h; Inert atmosphere;
DOI:10.2298/JSC090410108X

Reference yield:

: 120-14-9
3,4-dimethoxy-benzaldehyde

: 123-25-1
succinic acid diethyl ester

: 1220632-88-1
diethyl 2-(3,4-dimethoxybenzylidene)-3-(3,4-methylenedioxybenzyl)succinate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium ethanolate / ethanol / 4 h / Reflux

1.2: 24 h / Reflux

2.1: lithium diisopropyl amide / tetrahydrofuran / 0.33 h / -78 °C / Inert atmosphere

2.2: 2 h / -78 °C / Inert atmosphere

With sodium ethanolate; lithium diisopropyl amide; In tetrahydrofuran; ethanol;
DOI:10.2298/JSC090410108X

Reference yield:

: 1220632-88-1
diethyl 2-(3,4-dimethoxybenzylidene)-3-(3,4-methylenedioxybenzyl)succinate

: 1158909-02-4
(-)-5-{[(3R,4R)-4-(3,4-dimethoxybenzyl)-tetrahydro-3-furanyl]methyl}-1,3-benzodioxole

Guidance literature:: Multi-step reaction with 6 steps

1: water; sodium hydroxide / 3 h / Reflux

2: ethanol / 1 h / Reflux

3: sulfuric acid / benzene / 36 h / Reflux

4: palladium 10% on activated carbon; hydrogen / ethyl acetate / 12 h

5: lithium aluminium tetrahydride / tetrahydrofuran / 10 h

6: pyridine; p-toluenesulfonyl chloride / dichloromethane / 24 h / 20 °C

With pyridine; lithium aluminium tetrahydride; sulfuric acid; palladium 10% on activated carbon; water; hydrogen; p-toluenesulfonyl chloride; sodium hydroxide; In tetrahydrofuran; ethanol; dichloromethane; ethyl acetate; benzene;
DOI:10.2298/JSC090410108X