1-[2-(3-Bromo-2-hydroxypropoxy)phenyl]-3-phenyl-1-propanone

Base Information

• Chemical Name: 1-[2-(3-Bromo-2-hydroxypropoxy)phenyl]-3-phenyl-1-propanone
• CAS No.: 93885-34-8
• Molecular Formula: C₁₈H₁₉BrO₃
• Molecular Weight: 363.251
• Hs Code.: 2914700090
• Mol file: 93885-34-8.mol

Synonyms:1-[2-(3-Bromo-2-hydroxypropoxy)phenyl]-3-phenyl-1-propanone;2-(2Hydroxy-3bromopropoxy)-3-phenylpropiophenone

Chemical Property of 1-[2-(3-Bromo-2-hydroxypropoxy)phenyl]-3-phenyl-1-propanone

Chemical Property:

• PSA: 46.53000
• LogP: 3.63670
• Solubility.: Chloroform, Dichloromethane, Ethyl Acetate,

Purity/Quality:

97% ^*data from raw suppliers

1-[2-(3-Bromo-2-hydroxypropoxy)phenyl]-3-phenyl-1-propanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-[2-(3-Bromo-2-hydroxypropoxy)phenyl]-3-phenyl-1-propanone

There total 4 articles about 1-[2-(3-Bromo-2-hydroxypropoxy)phenyl]-3-phenyl-1-propanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

o-hydroxyacetophenone (118-93-4,104809-67-8) → 1-[2-(3-Bromo-2-hydroxy-propoxy)-phenyl]-3-phenyl-propan-1-one (93885-34-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) 50percent NaOH, 2.) H₂ / 2.) Pd-charcoal / 1.) methanol, r.t., 60 h, 2.) methanol, normal pressure

3: HBr

With sodium hydroxide; hydrogen bromide; hydrogen; palladium on activated charcoal;

Reference yield:

benzaldehyde (100-52-7) → 1-[2-(3-Bromo-2-hydroxy-propoxy)-phenyl]-3-phenyl-propan-1-one (93885-34-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) 50percent NaOH, 2.) H₂ / 2.) Pd-charcoal / 1.) methanol, r.t., 60 h, 2.) methanol, normal pressure

3: HBr

With sodium hydroxide; hydrogen bromide; hydrogen; palladium on activated charcoal;

Reference yield:

1-(2-(oxiran-2-ylmethoxy)phenyl)-3-phenylpropan-1-one (22525-95-7) → 1-[2-(3-Bromo-2-hydroxy-propoxy)-phenyl]-3-phenyl-propan-1-one (93885-34-8)

Guidance literature:

With hydrogen bromide;

upstream raw materials:

1-(2-(oxiran-2-ylmethoxy)phenyl)-3-phenylpropan-1-one

2'-hydroxy-3-phenylpropiophenone

o-hydroxyacetophenone

benzaldehyde