Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI)

Base Information

• Chemical Name: Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI)
• CAS No.: 98489-36-2
• Molecular Formula: C8H12 N2
• Molecular Weight: 136.197
• Hs Code.: 2933399090
• Mol file: 98489-36-2.mol

Synonyms:Pyridine,5-(aminomethyl)-2,4-dimethyl- (6CI); 3-(Aminomethyl)-4,6-dimethylpyridine

Chemical Property of Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI)

Chemical Property:

• PSA: 38.91000
• LogP: 1.85740

Purity/Quality:

97% ^*data from raw suppliers

1-(4,6-dimethyl-3-pyridinyl)methanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI)

There total 9 articles about Pyridine, 5-(aminomethyl)-2,4-dimethyl- (6CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

S-methyl-4,6-dimethyl-2-thiopyridine-3-carbonitrile (72456-86-1) → 1-(4,6-dimethylpyridin-3-yl)methanamine (98489-36-2) + 3-cyano-4,6-dimethylpyridine (6623-21-8) + 3-aminomethyl-4,6-dimethyl-2-methylthiopyridine (445471-13-6)

Guidance literature:

With hydrogen; nickel; In ethanol; at 130 ℃; under 152000 Torr;

DOI:10.1007/s11172-006-0158-6

Reference yield:

2-chloro-4,6-dimethylnicotinonitrile (14237-71-9) → 1-(4,6-dimethylpyridin-3-yl)methanamine (98489-36-2) + 3-cyano-4,6-dimethylpyridine (6623-21-8)

Guidance literature:

Reference yield:

2-chloro-4,6-dimethylnicotinonitrile (14237-71-9) → 1-(4,6-dimethylpyridin-3-yl)methanamine (98489-36-2)

Guidance literature:

With hydrogenchloride; palladium on activated charcoal; under 1029.7 Torr; Hydrogenation;

DOI:10.1021/ja01169a093

upstream raw materials:

2-chloro-4,6-dimethylnicotinonitrile

6-methyl-4-methoxymethyl-3-cyano-2-chloropyridine

S-methyl-4,6-dimethyl-2-thiopyridine-3-carbonitrile

2-hydroxy-4,6-dimethyl-3-carbonitrile

Downstream raw materials:

pyridine-2,4,5-tricarboxylic acid

(2R,3S)-3-(6-((4,6-dimethylpyridin-3-ylmethyl)amino)-9-isopropyl-9H-purin-2-ylamino)pentan-2-ol