C₂₈H₃₈O₅

Base Information

• Chemical Name: C₂₈H₃₈O₅
• CAS No.: 1360998-99-7
• Molecular Formula: C₂₈H₃₈O₅
• Molecular Weight: 454.607
• Mol file: 1360998-99-7.mol

Synonyms:C₂₈H₃₈O₅

Chemical Property of C₂₈H₃₈O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₃₈O₅

There total 4 articles about C₂₈H₃₈O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C22H30O4 (1360998-97-5) + 4-(diethoxyphosphoryl)-but-2-enoic acid ethyl ester (10236-14-3) → C28H38O5 (1360998-99-7)

Guidance literature:

4-(diethoxyphosphoryl)-but-2-enoic acid ethyl ester; With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 1h; Inert atmosphere;

C₂₂H₃₀O₄; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmcl.2011.12.137

Reference yield:

Bicyclo<2.2.2>octane-1,4-dimethanol (826-45-9) → C28H38O5 (1360998-99-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 20 °C

3.1: sodium hydride / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

3.2: 0 - 20 °C / Inert atmosphere

With sodium hydride; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 3.1: Horner-Wadsworth-Emmons type reaction / 3.2: Horner-Wadsworth-Emmons type reaction;

DOI:10.1016/j.bmcl.2011.12.137

Reference yield:

Bicyclo<2.2.2.>octan-1,4-dicarbonsauere-ethylester (1659-75-2) → C28H38O5 (1360998-99-7)

Guidance literature:

Multi-step reaction with 4 steps

1.1: lithium aluminium tetrahydride / diethyl ether / 4 h / Inert atmosphere; Reflux

2.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C / Inert atmosphere

2.2: 0 - 20 °C / Inert atmosphere

3.1: pyridinium chlorochromate / dichloromethane / 2.5 h / 20 °C

4.1: sodium hydride / tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

4.2: 0 - 20 °C / Inert atmosphere

With lithium aluminium tetrahydride; sodium hydride; pyridinium chlorochromate; In tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide; 4.1: Horner-Wadsworth-Emmons type reaction / 4.2: Horner-Wadsworth-Emmons type reaction;

DOI:10.1016/j.bmcl.2011.12.137

upstream raw materials:

C₂₂H₃₂O₄

C₂₂H₃₀O₄

4-(diethoxyphosphoryl)-but-2-enoic acid ethyl ester

Bicyclo<2.2.2>octane-1,4-dimethanol

Downstream raw materials:

C₃₀H₄₈O₄