8-Methoxy-5,6-dihydrobenzo[h]quinazolin-2-amine

Base Information

Chemical Name:8-Methoxy-5,6-dihydrobenzo[h]quinazolin-2-amine
CAS No.:14623-49-5
Molecular Formula:C₁₃H₁₃N₃O
Molecular Weight:227.266
Hs Code.:
NSC Number:99375
DSSTox Substance ID:DTXSID20295037
Wikidata:Q82034708
ChEMBL ID:CHEMBL1484205
Mol file:14623-49-5.mol

Synonyms:14623-49-5;8-methoxy-5,6-dihydrobenzo[h]quinazolin-2-amine;8-methoxy-5H,6H-benzo[h]quinazolin-2-amine;2-Amino-8-methoxy-5,6-dihydrobenzo[h]quinazoline;MFCD04126363;NSC99375;MLS000696479;CHEMBL1484205;DTXSID20295037;HMS2725F04;AC9672;NSC-99375;AKOS012858508;SMR000336585;SY264208;CS-0361153;5,6-dihydro-8-methoxybenzo[h]quinazolin-2-amine;9W-0327;SR-01000306942;SR-01000306942-1

Suppliers and Price of 8-Methoxy-5,6-dihydrobenzo[h]quinazolin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
8-METHOXY-5,6-DIHYDROBENZO[H]QUINAZOLIN-2-AMINE 95.00%
1MG
$ 647.61

AK Scientific
8-Methoxy-5,6-dihydrobenzo[h]quinazolin-2-amine
1g
$ 937.00

Total 3 raw suppliers

Chemical Property of 8-Methoxy-5,6-dihydrobenzo[h]quinazolin-2-amine

Chemical Property:

Vapor Pressure:1.32E-09mmHg at 25°C
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:227.105862047
Heavy Atom Count:17
Complexity:273

Purity/Quality:

99% ^*data from raw suppliers

8-METHOXY-5,6-DIHYDROBENZO[H]QUINAZOLIN-2-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C3=NC(=NC=C3CC2)N

Technology Process of 8-Methoxy-5,6-dihydrobenzo[h]quinazolin-2-amine

There total 4 articles about 8-Methoxy-5,6-dihydrobenzo[h]quinazolin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.6%

: 50-01-1
guanidine hydrochloride

: (Z)-2-((dimethylamino)methylene)-6-methoxy-3,4-dihydronaphthalene-1(2H)-one

: 14623-49-5
8-methoxy-5,6-dihydrobenzo[h]quinazolin-2-amine

Guidance literature:: With sodium carbonate; at 120 ℃; for 8h;

Reference yield: 72.6%

: 14623-48-4
2-Dimethylaminomethylen-6-methoxy-1-tetralon

: 50-01-1
guanidine hydrochloride

: 14623-49-5
8-methoxy-5,6-dihydrobenzo[h]quinazolin-2-amine

Guidance literature:: With sodium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 8h;
DOI:10.1111/cbdd.13992

Reference yield:

: 1078-19-9
6-methoxy-3,4-dihydro-1(2H)-naphthalenone

: 14623-49-5
8-methoxy-5,6-dihydrobenzo[h]quinazolin-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 12 h / 110 °C

2: sodium carbonate / 8 h / 120 °C

With sodium carbonate; In N,N-dimethyl-formamide;