(2R,3R)-4-methylene-2-phenyl-1-((S)-toluene-4-sulfinyl)-pyrrolidine-3-carbothioic acid S-tert-butyl ester

Base Information

Chemical Name:(2R,3R)-4-methylene-2-phenyl-1-((S)-toluene-4-sulfinyl)-pyrrolidine-3-carbothioic acid S-tert-butyl ester
CAS No.:1073146-88-9
Molecular Formula:C₂₃H₂₇NO₂S₂
Molecular Weight:413.605
Hs Code.:

Synonyms:(2R,3R)-4-methylene-2-phenyl-1-((S)-toluene-4-sulfinyl)-pyrrolidine-3-carbothioic acid S-tert-butyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3R)-4-methylene-2-phenyl-1-((S)-toluene-4-sulfinyl)-pyrrolidine-3-carbothioic acid S-tert-butyl ester

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Technology Process of (2R,3R)-4-methylene-2-phenyl-1-((S)-toluene-4-sulfinyl)-pyrrolidine-3-carbothioic acid S-tert-butyl ester

There total 1 articles about (2R,3R)-4-methylene-2-phenyl-1-((S)-toluene-4-sulfinyl)-pyrrolidine-3-carbothioic acid S-tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 1073146-55-0
2-methylene-cyclopropanecarbothioic acid S-tert-butyl ester

: 153277-49-7
(S)-N-benzylidene-4-toluenesulfinamide

: C₉H₁₅IOS

: C₂₃H₂₇NO₂S₂

: (2S,3S)-4-methylene-2-phenyl-1-((S)-toluene-4-sulfinyl)-pyrrolidine-3-carbothioic acid S-tert-butyl ester

: 1073146-88-9
(2R,3R)-4-methylene-2-phenyl-1-((S)-toluene-4-sulfinyl)-pyrrolidine-3-carbothioic acid S-tert-butyl ester

Guidance literature:: With magnesium iodide; In tetrahydrofuran; at 20 ℃; for 18.3333h; optical yield given as %de; stereoselective reaction; Inert atmosphere; Reflux;
DOI:10.1021/jo802049u