2, 5-diamino-7-(methylthio)-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile

Base Information

• Chemical Name: 2, 5-diamino-7-(methylthio)-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile
• CAS No.: 155375-38-5
• Molecular Formula: C₁₄H₁₂N₈S
• Molecular Weight: 324.369
• Mol file: 155375-38-5.mol

Synonyms:2, 5-diamino-7-(methylthio)-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile

Chemical Property of 2, 5-diamino-7-(methylthio)-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2, 5-diamino-7-(methylthio)-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile

There total 3 articles about 2, 5-diamino-7-(methylthio)-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

[Bis(methylthio)methylene]malononitrile (5147-80-8) + 3,5-diamino-4-phenylazopyrazole (3656-02-8) → 2, 5-diamino-7-(methylthio)-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile (155375-38-5)

Guidance literature:

In N,N-dimethyl-formamide; at 154 ℃; for 0.166667h; Microwave irradiation;

DOI:10.1080/15257770.2016.1202964

Reference yield:

2,5-diamino-7-mercapto-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile + methyl iodide (74-88-4) → 2, 5-diamino-7-(methylthio)-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile (155375-38-5)

Guidance literature:

2,5-diamino-7-mercapto-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile; With sodium ethanolate; for 0.5h; Reflux;

methyl iodide; for 3h; Reflux;

DOI:10.1080/15257770.2016.1202964

Reference yield:

3,5-diamino-4-phenylazopyrazole (3656-02-8) → 2, 5-diamino-7-(methylthio)-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-6-carbonitrile (155375-38-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N,N-dimethyl-formamide / 0.17 h / 154 °C / Microwave irradiation

2.1: sodium ethanolate / 0.5 h / Reflux

2.2: 3 h / Reflux

With sodium ethanolate; In N,N-dimethyl-formamide;

DOI:10.1080/15257770.2016.1202964

upstream raw materials:

[Bis(methylthio)methylene]malononitrile

3,5-diamino-4-phenylazopyrazole

methyl iodide