Pyridine, 2,3,6-triamino-4-chloro- (6CI)

Base Information

• Chemical Name: Pyridine, 2,3,6-triamino-4-chloro- (6CI)
• CAS No.: 98021-93-3
• Molecular Formula: C₅H₇ClN₄
• Molecular Weight: 158.59
• Mol file: 98021-93-3.mol

Synonyms:Pyridine,2,3,6-triamino-4-chloro- (6CI); NSC 146822

Chemical Property of Pyridine, 2,3,6-triamino-4-chloro- (6CI)

Chemical Property:

• PSA: 90.95000
• LogP: 2.22520

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyridine, 2,3,6-triamino-4-chloro- (6CI)

There total 5 articles about Pyridine, 2,3,6-triamino-4-chloro- (6CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

(E)-4-chloro-3-((4-chlorophenyl)diazenyl)pyridine-2,6-diamine → 4-chloropyridine-2,3,6-triamine (98021-93-3)

Guidance literature:

With acetic acid; zinc; In ethanol; at 70 ℃; for 2h;

Reference yield:

4-chloropyridine-2,6-diamine (6309-00-8) → 4-chloropyridine-2,3,6-triamine (98021-93-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous HCl

2: aqueous Na₂S₂O₄; ethanol

With hydrogenchloride; sodium dithionite; ethanol;

DOI:10.1021/ja01597a074

Reference yield:

N,N'-(4-chloro-pyridine-2,6-diyl)-bis-carbamic acid diethyl ester (63708-78-1) → 4-chloropyridine-2,3,6-triamine (98021-93-3)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanolic KOH

2: Erwaermen des Reaktionsprodukts mit Na₂S₂O₄ in H₂O

With potassium hydroxide;

DOI:10.1021/ja01597a074

upstream raw materials:

4-chloropyridine-2,6-diamine

4-sulfobenzenediazonium

4-chloro-3-phenylazo-pyridine-2,6-diyldiamine

N,N'-(4-chloro-pyridine-2,6-diyl)-bis-carbamic acid diethyl ester

Downstream raw materials:

N-(7-chloro-1(3)H-imidazo[4,5-b]pyridin-5-yl)-formamide

7-chloro-3H-[1,2,3]triazolo[4,5-b]pyridin-5-amine