C₂₃H₃₆OS₄Si

Base Information

• Chemical Name: C₂₃H₃₆OS₄Si
• CAS No.: 1596301-78-8
• Molecular Formula: C₂₃H₃₆OS₄Si
• Molecular Weight: 484.888
• Mol file: 1596301-78-8.mol

Synonyms:C₂₃H₃₆OS₄Si

Chemical Property of C₂₃H₃₆OS₄Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₂₃H₃₆OS₄Si

There total 4 articles about C₂₃H₃₆OS₄Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

C12H22OS2Si + 2-lithio-2-trimethylsilyl-1,3-dithiane (34410-04-3) + benzyl bromide (100-39-0) → C23H36OS4Si (1596301-78-8)

Guidance literature:

C₁₂H₂₂OS₂Si; 2-lithio-2-trimethylsilyl-1,3-dithiane; In diethyl ether; at -40 - 20 ℃; for 2h; Inert atmosphere;

benzyl bromide; With hydrogenchloride; N,N,N,N,N,N-hexamethylphosphoric triamide; In diethyl ether; water; at 20 ℃; Inert atmosphere;

DOI:10.1002/anie.201309270

Reference yield:

C5H6O2 → C23H36OS4Si (1596301-78-8)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / Inert atmosphere

2.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 1 h / 0 °C / Inert atmosphere

3.1: N,N,N,N,N,N-hexamethylphosphoric triamide; tert.-butyl lithium / tetrahydrofuran; pentane / 0.25 h / -78 - -45 °C / Inert atmosphere

3.2: 1 h / -25 °C / Inert atmosphere

4.1: diethyl ether / 2 h / -40 - 20 °C / Inert atmosphere

4.2: 20 °C / Inert atmosphere

With N,N,N,N,N,N-hexamethylphosphoric triamide; carbon tetrabromide; tetrabutyl ammonium fluoride; tert.-butyl lithium; triphenylphosphine; In tetrahydrofuran; diethyl ether; dichloromethane; pentane; 2.1: |Appel Halogenation;

DOI:10.1002/anie.201309270

Reference yield:

(2S,3R)-3-ethenyloxirane-2-methanol (78260-12-5,102419-62-5,121521-24-2,121521-25-3,137252-92-7) → C23H36OS4Si (1596301-78-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 1 h / 0 °C / Inert atmosphere

2.1: N,N,N,N,N,N-hexamethylphosphoric triamide; tert.-butyl lithium / tetrahydrofuran; pentane / 0.25 h / -78 - -45 °C / Inert atmosphere

2.2: 1 h / -25 °C / Inert atmosphere

3.1: diethyl ether / 2 h / -40 - 20 °C / Inert atmosphere

3.2: 20 °C / Inert atmosphere

With N,N,N,N,N,N-hexamethylphosphoric triamide; carbon tetrabromide; tert.-butyl lithium; triphenylphosphine; In tetrahydrofuran; diethyl ether; dichloromethane; pentane; 1.1: |Appel Halogenation;

DOI:10.1002/anie.201309270

upstream raw materials:

2-lithio-2-trimethylsilyl-1,3-dithiane

benzyl bromide

(2S,3R)-3-ethenyloxirane-2-methanol