(3S,4S)-1-(3-(2-aminopyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol

Base Information

Chemical Name:(3S,4S)-1-(3-(2-aminopyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol
CAS No.:1318802-66-2
Molecular Formula:C₁₄H₁₆N₄O₃
Molecular Weight:288.306
Hs Code.:

Synonyms:(3S,4S)-1-(3-(2-aminopyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol

Suppliers and Price of (3S,4S)-1-(3-(2-aminopyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3S,4S)-1-(3-(2-aminopyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol

Chemical Property:

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Technology Process of (3S,4S)-1-(3-(2-aminopyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol

There total 10 articles about (3S,4S)-1-(3-(2-aminopyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: C₂₅H₃₀N₄O₅

: 1318802-66-2
(3S,4S)-1-(3-(2-aminopyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol

Guidance literature:: With boron tribromide; In dichloromethane;
DOI:10.1016/j.bmcl.2011.05.081

Reference yield:

: 126656-56-2
C₁₇H₁₇NO₃

: 1318802-66-2
(3S,4S)-1-(3-(2-aminopyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol

Guidance literature:: Multi-step reaction with 7 steps

2: dmap; triethylamine

3: water; sodium hydroxide

4: sodium ethanolate

5: trifluoroacetic acid / dichloromethane

6: triethylamine / butan-1-ol

7: boron tribromide / dichloromethane

With dmap; water; sodium ethanolate; boron tribromide; triethylamine; trifluoroacetic acid; sodium hydroxide; In dichloromethane; butan-1-ol;
DOI:10.1016/j.bmcl.2011.05.081

Reference yield:

: C₂₅H₃₀N₂O₅

: 1318802-66-2
(3S,4S)-1-(3-(2-aminopyrimidin-4-yl)-4-hydroxyphenyl)pyrrolidine-3,4-diol

Guidance literature:: Multi-step reaction with 5 steps

1: water; sodium hydroxide

2: sodium ethanolate

3: trifluoroacetic acid / dichloromethane

4: triethylamine / butan-1-ol

5: boron tribromide / dichloromethane

With water; sodium ethanolate; boron tribromide; triethylamine; trifluoroacetic acid; sodium hydroxide; In dichloromethane; butan-1-ol;
DOI:10.1016/j.bmcl.2011.05.081