(-)-5,11,17,23-tetra-tert-butyl-25-ethoxy-26,28-dihydroxy-27-<(1R,2S,5R)menthyloxycarbonylmethoxy>calix<4>arene

Base Information

• Chemical Name: (-)-5,11,17,23-tetra-tert-butyl-25-ethoxy-26,28-dihydroxy-27-<(1R,2S,5R)menthyloxycarbonylmethoxy>calix<4>arene
• CAS No.: 175671-51-9
• Molecular Formula: C₅₈H₈₀O₆
• Molecular Weight: 873.27
• Mol file: 175671-51-9.mol

Synonyms:(-)-5,11,17,23-tetra-tert-butyl-25-ethoxy-26,28-dihydroxy-27-<(1R,2S,5R)menthyloxycarbonylmethoxy>calix<4>arene

Chemical Property of (-)-5,11,17,23-tetra-tert-butyl-25-ethoxy-26,28-dihydroxy-27-<(1R,2S,5R)menthyloxycarbonylmethoxy>calix<4>arene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-5,11,17,23-tetra-tert-butyl-25-ethoxy-26,28-dihydroxy-27-<(1R,2S,5R)menthyloxycarbonylmethoxy>calix<4>arene

There total 1 articles about (-)-5,11,17,23-tetra-tert-butyl-25-ethoxy-26,28-dihydroxy-27-<(1R,2S,5R)menthyloxycarbonylmethoxy>calix<4>arene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

(1R,2S,5R)-menthol bromoacetate (16832-20-5,32815-12-6,55284-67-8) + 5,11,17,23-Tetrakis(1,1-dimethylethyl)-28-ethoxypentacyclo<19.3.1.13,7.19,13.115,19>octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecene-25,26,27-triol (134225-77-7,138331-89-2) → (-)-5,11,17,23-tetra-tert-butyl-25-ethoxy-26,28-dihydroxy-27-<(1R,2S,5R)menthyloxycarbonylmethoxy>calix<4>arene (175671-51-9)

Guidance literature:

With potassium carbonate; In acetonitrile; for 12h; Heating;

DOI:10.1039/DT9960000513

Reference yield: 78.0%

chloro-diphenylphosphine (1079-66-9,74391-44-9) + (-)-5,11,17,23-tetra-tert-butyl-25-ethoxy-26,28-dihydroxy-27-<(1R,2S,5R)menthyloxycarbonylmethoxy>calix<4>arene (175671-51-9) → (-)-5,11,17,23-tetra-tert-butyl-25,27-bis(diphenylphosphinooxy)-26-ethoxy-28-((1R,2S,5R)menthyloxycarbonylmethoxy)calix[4]arene

Guidance literature:

With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

DOI:10.1039/DT9960000513

Reference yield:

chloro-diphenylphosphine (1079-66-9,74391-44-9) + (-)-5,11,17,23-tetra-tert-butyl-25-ethoxy-26,28-dihydroxy-27-<(1R,2S,5R)menthyloxycarbonylmethoxy>calix<4>arene (175671-51-9) → (-)-5,11,17,23-tetrakis-tert-butyl-25,27-bis(diphenylphosphinooxy)-26-ethoxy-28-[(1R,2S,5R)menthyloxycarbonylmethoxy]calix[4]arene (175671-53-1)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, -78 deg, 2.) THF, -78 deg C;

DOI:10.1039/c39930000604

upstream raw materials:

(1R,2S,5R)-menthol bromoacetate

5,11,17,23-Tetrakis(1,1-dimethylethyl)-28-ethoxypentacyclo<19.3.1.1^3,7.1^9,13.1^15,19>octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecene-25,26,27-triol

Downstream raw materials:

(-)-5,11,17,23-tetrakis-tert-butyl-25,27-bis(diphenylphosphinooxy)-26-ethoxy-28-[(1R,2S,5R)menthyloxycarbonylmethoxy]calix[4]arene