BENZYL 2-ACETAMIDO-2-DEOXY-6-O-(BETA-D-GALACTOPYRANOSYL)-ALPHA-D-GALACTOPYRANOSIDE

Base Information

• Chemical Name: BENZYL 2-ACETAMIDO-2-DEOXY-6-O-(BETA-D-GALACTOPYRANOSYL)-ALPHA-D-GALACTOPYRANOSIDE
• CAS No.: 93496-44-7
• Molecular Formula: C₂₁H₃₁NO₁₁
• Molecular Weight: 473.477
• Mol file: 93496-44-7.mol

Synonyms:BENZYL 2-ACETAMIDO-2-DEOXY-6-O-(BETA-D-GALACTOPYRANOSYL)-ALPHA-D-GALACTOPYRANOSIDE

Chemical Property of BENZYL 2-ACETAMIDO-2-DEOXY-6-O-(BETA-D-GALACTOPYRANOSYL)-ALPHA-D-GALACTOPYRANOSIDE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 219-224°C dec.
• Refractive Index: 1.624
• Boiling Point: 798.993°C at 760 mmHg
• Flash Point: 437.015°C
• PSA: 187.40000
• Density: 1.496g/cm³
• LogP: -2.63800
• Storage Temp.: -20°C Freezer
• Solubility.: Methanol (Slightly), Water (Slightly)

Purity/Quality:

95% ^*data from raw suppliers

Benzyl2-Acetamido-2-deoxy-6-O-(β-D-galactopyranosyl)-α-D-galactopyranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BENZYL 2-ACETAMIDO-2-DEOXY-6-O-(BETA-D-GALACTOPYRANOSYL)-ALPHA-D-GALACTOPYRANOSIDE

There total 4 articles about BENZYL 2-ACETAMIDO-2-DEOXY-6-O-(BETA-D-GALACTOPYRANOSYL)-ALPHA-D-GALACTOPYRANOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

benzyl 2-acetamido-2-deoxy-α-D-galactopyranoside (3554-93-6,347411-88-5) + 4-nitrophenyl-β-D-galactopyranoside (3150-24-1) → (2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-α-D-galactopyranosyl)-O-benzyl glycoside (3554-96-9) + Galβ1→6GalNAcα-Bn (93496-44-7)

Guidance literature:

With sodium phosphate; β-galactosidase; In water; N,N-dimethyl-formamide; at 37 ℃; for 3h; Product distribution; effect of donor/acceptor ratio, also immobilized β-galactosidase;

DOI:10.1271/bbb.62.1313

Reference yield:

benzyl 2-acetamido-3-O-acetyl-2-deoxy-α-D-galactopyranoside (3554-95-8) → Galβ1→6GalNAcα-Bn (93496-44-7)

Guidance literature:

Multi-step reaction with 2 steps

1: mercuric cyanide / benzene; nitromethane / 48 h / 60 °C

2: 0.5 M sodium methoxide, methanol

With methanol; sodium methylate; mercury(II) cyanide; In nitromethane; benzene;

DOI:10.1016/0008-6215(84)85248-9

Reference yield:

1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside (3068-32-4) → Galβ1→6GalNAcα-Bn (93496-44-7)

Guidance literature:

Multi-step reaction with 2 steps

1: mercuric cyanide / benzene; nitromethane / 48 h / 60 °C

2: 0.5 M sodium methoxide, methanol

With methanol; sodium methylate; mercury(II) cyanide; In nitromethane; benzene;

DOI:10.1016/0008-6215(84)85248-9

upstream raw materials:

Acetic acid (2R,3R,4S,5S,6R)-3,5-diacetoxy-2-((2R,3R,4R,5R,6S)-4-acetoxy-5-acetylamino-6-benzyloxy-3-hydroxy-tetrahydro-pyran-2-ylmethoxy)-6-acetoxymethyl-tetrahydro-pyran-4-yl ester

benzyl 2-acetamido-2-deoxy-α-D-galactopyranoside

4-nitrophenyl-β-D-galactopyranoside

benzyl 2-acetamido-3-O-acetyl-2-deoxy-α-D-galactopyranoside

Downstream raw materials:

2-acetamido-2-deoxy-6-O-β-D-galactopyranosyl-β-D-galactopyranose

2-acetamido-2-deoxy-6-O-β-D-galactopyranosyl-α-D-galactopyranose