tert-butyl-(2,3-epoxybutyl)-phenyl phosphine oxide

Base Information

• Chemical Name: tert-butyl-(2,3-epoxybutyl)-phenyl phosphine oxide
• CAS No.: 228404-68-0
• Molecular Formula: C₁₄H₂₁O₂P
• Molecular Weight: 252.293
• Mol file: 228404-68-0.mol

Synonyms:tert-butyl-(2,3-epoxybutyl)-phenyl phosphine oxide

Chemical Property of tert-butyl-(2,3-epoxybutyl)-phenyl phosphine oxide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of tert-butyl-(2,3-epoxybutyl)-phenyl phosphine oxide

There total 2 articles about tert-butyl-(2,3-epoxybutyl)-phenyl phosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(2-butenyl)-tert-butyl-phenyl phosphine oxide (133201-82-8) → tert-butyl-(2,3-epoxybutyl)-phenyl phosphine oxide (228404-68-0)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 6h; Heating;

DOI:10.1080/10426509808029677

Reference yield:

tert-Butylphenylphosphine oxide (98976-30-8,57956-51-1,6057-79-0,82945-11-7) → tert-butyl-(2,3-epoxybutyl)-phenyl phosphine oxide (228404-68-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / NaH / tetrahydrofuran / 2 h / 20 °C

2: 85 percent / MCPBA / CH₂Cl₂ / 6 h / Heating

With sodium hydride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; 1: Substitution / 2: Epoxidation;

DOI:10.1080/10426509808029677

Reference yield: 90.0%

tert-butyl-(2,3-epoxybutyl)-phenyl phosphine oxide (228404-68-0) → tert-butyl-(3-hydroxy-1-butenyl)-phenyl phosphine oxide (228404-69-1)

Guidance literature:

With sodium methylate; In methanol;

DOI:10.1080/10426509808029677

upstream raw materials:

(2-butenyl)-tert-butyl-phenyl phosphine oxide

tert-Butylphenylphosphine oxide

Downstream raw materials:

tert-butyl-(3-hydroxy-1-butenyl)-phenyl phosphine oxide