N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-benzylguanidine

Base Information

Chemical Name:N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-benzylguanidine
CAS No.:1224570-59-5
Molecular Formula:C₂₀H₁₉Cl₂N₅O₂
Molecular Weight:432.309
Hs Code.:

Synonyms:N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-benzylguanidine

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Chemical Property of N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-benzylguanidine

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Technology Process of N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-benzylguanidine

There total 2 articles about N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-benzylguanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 857672-28-7
1-isopropyl-2-methylsulfanyl-1H-imidazole-4,5-dione

: 17826-48-1
N-benzyl-N'-(3,4-dichlorophenyl)-guanidine

: 1224570-59-5
N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-benzylguanidine

Guidance literature:: In chloroform; at 100 ℃; Sealed tube;
DOI:10.1016/j.bmc.2010.12.028

Reference yield:

: 57005-11-5
1-(3,4-dichlorophenyl)-2-methylisothiourea hydrogeniodide

: 100-46-9
benzylamine

: 1224570-59-5
N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-benzylguanidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: methanol / 18 h / 80 - 100 °C / Sealed tube

1.2: Saturated solution

2.1: chloroform / 100 °C / Sealed tube

In methanol; chloroform;
DOI:10.1016/j.bmc.2010.12.028