57005-11-5

Basic information

• Product Name: 1-(3,4-Dichloro-phenyl)-2-methyl-isothiourea; hydriodide
• Synonyms: 1-(3,4-Dichloro-phenyl)-2-methyl-isothiourea; hydriodide
• CAS NO: 57005-11-5
• Molecular Weight: 363.049
• Mol File: 57005-11-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-(3,4-Dichloro-phenyl)-2-methyl-isothiourea; hydriodide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4-Dichloro-phenyl)-2-methyl-isothiourea; hydriodide(57005-11-5)
• EPA Substance Registry System: 1-(3,4-Dichloro-phenyl)-2-methyl-isothiourea; hydriodide(57005-11-5)

Safety Data

• Hazardous Substances Data: 57005-11-5(Hazardous Substances Data)

Upstream product

• 19250-09-0 3,4-dichlorophenylthiourea 
• 74-88-4 methyl iodide 
• 95-76-1 m,p-dichloroaniline 
• 19249-85-5 N-benzoyl-N’-(3,4-dichlorophenyl)thiourea 

Downstream Products

• 1224570-59-5 N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-benzylguanidine 
• 17826-48-1 N-benzyl-N'-(3,4-dichlorophenyl)-guanidine 
• 57004-87-2 N-(isopropyl)-N'-(3,4-dichlorophenyl)-guanidine 
• 1224570-55-1 N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-isopropylguanidine 
• 1224570-56-2 N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-t-butylguanidine 
• 1224570-53-9 N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-ethylguanidine 
• 1224570-51-7 N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-methylguanidine 
• 17826-33-4 N-ethyl-N'-(3,4-dichlorophenyl)-guanidine 
• 1224570-77-7 N-(2-adamantyl)-N'-(3,4-dichlorophenyl)-guanidine 
• 1224570-58-4 N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-phenylguanidine 
• 1224570-61-9 N-(3,4-dichloro-phenyl)-N'-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-N''-N-hexyl-guanidine 
• 1224570-76-6 N-(n-hexyl)-N'-(3,4-dichlorophenyl)-guanidine 
• 1224570-57-3 N-(3,4-dichloro-phenyl)-N'-(2,2-dimethyl-propyl)-N''-(1-isopropyl-4,5-dioxo-4,5-dihydro-1H-imidazol-2-yl)-guanidine 
• 1224570-75-5 N-neopenty-N'-(3,4-dichlorophenyl)-guanidine 

Relevant articles and documents

Synthesis and biological evaluation of 3-amino-1,2,4-triazole derivatives as potential anticancer compounds

Two series of compounds carrying 3-amino-1,2,4-triazole scaffold were synthesized and evaluated for their anticancer activity against a panel of cancer cell lines using XTT assay. The 1,2,4-triazole synthesis was revisited for the first series of pyridyl derivatives. The biological results revealed the efficiency of the 3-amino-1,2,4-triazole core that could not be replaced and a clear beneficial effect of a 3-bromophenylamino moiety in position 3 of the triazole for both series (compounds 2.6 and 4.6) on several cell lines tested. Moreover, our results point out an antiangiogenic activity of these compounds. Overall, the 5-aryl-3-phenylamino-1,2,4-triazole structure has promising dual anticancer activity.

Unambiguous synthesis and prophylactic antimalarial activities of imidazolidinedione derivatives

WR182393, a guanidinoimidazolidinedione derivatives with potent causal prophylactic antimalarial activity by intramuscular injection, was previouly prepared by treatment of chloroproguanil and diethyl oxalate, yielding a mixture of two closely related iso

New antiarrhythmic agents. Piperazine guanidine derivatives

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