[(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-carbamic acid benzyl ester

Base Information

• Chemical Name: [(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-carbamic acid benzyl ester
• CAS No.: 1053635-61-2
• Molecular Formula: C₃₀H₄₃N₃O₄
• Molecular Weight: 509.689

Synonyms:[(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-carbamic acid benzyl ester

Chemical Property of [(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-carbamic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-carbamic acid benzyl ester

There total 4 articles about [(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-benzyl (4-chloro-3-oxo-1-phenylbutan-2-yl)carbamate (26049-94-5) → [(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-carbamic acid benzyl ester (1053635-61-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 43 percent / NaBH₄ / methanol; tetrahydrofuran

2: 90 percent / KOH / ethanol

3: propan-2-ol / Heating

4: CH₂Cl₂ / Ambient temperature

With potassium hydroxide; sodium tetrahydroborate; In tetrahydrofuran; methanol; ethanol; dichloromethane; isopropyl alcohol;

DOI:10.1021/jm00054a014

Reference yield:

N-benzyloxycarbonyl-3(S)-amino-1-chloro-4-phenyl-2(S)-butanol (128018-43-9) → [(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-carbamic acid benzyl ester (1053635-61-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / KOH / ethanol

2: propan-2-ol / Heating

3: CH₂Cl₂ / Ambient temperature

With potassium hydroxide; In ethanol; dichloromethane; isopropyl alcohol;

DOI:10.1021/jm00054a014

Reference yield:

N-benzyloxycarbonyl-3(S)-amino-1,2(S)epoxy-4-phenylbutane (128018-44-0) → [(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-carbamic acid benzyl ester (1053635-61-2)

Guidance literature:

Multi-step reaction with 2 steps

1: propan-2-ol / Heating

2: CH₂Cl₂ / Ambient temperature

In dichloromethane; isopropyl alcohol;

DOI:10.1021/jm00054a014

upstream raw materials:

N-benzyloxycarbonyl-3(S)-amino-1,2(S)epoxy-4-phenylbutane

(S)-benzyl (4-chloro-3-oxo-1-phenylbutan-2-yl)carbamate

N-benzyloxycarbonyl-3(S)-amino-1-chloro-4-phenyl-2(S)-butanol

cyclohexylmethylamine

Downstream raw materials:

1-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-3-tert-butyl-1-cyclohexylmethyl-urea

{(S)-1-[(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propylcarbamoyl]-2-carbamoyl-ethyl}-carbamic acid benzyl ester

(S)-2-Amino-N¹-[(1S,2R)-1-benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-succinamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1053635-61-2 [(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-carbamic acid benzyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send