(R)-N-(heptan-2-yl)acetamide

Base Information

• Chemical Name: (R)-N-(heptan-2-yl)acetamide
• CAS No.: 50789-57-6
• Molecular Formula: C₉H₁₉NO
• Molecular Weight: 157.256
• Mol file: 50789-57-6.mol

Synonyms:(R)-N-(heptan-2-yl)acetamide

Chemical Property of (R)-N-(heptan-2-yl)acetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-N-(heptan-2-yl)acetamide

There total 4 articles about (R)-N-(heptan-2-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

ethyl acetate (141-78-6) + 2-heptylamine (123-82-0) → (S)-2-heptylamine (123-82-0,6240-90-0,7795-34-8,44745-29-1) + (R)-N-(heptan-2-yl)acetamide (50789-57-6)

Guidance literature:

With Candida antarctica (Novozym 435); In diethyl ether; at 21 ℃; for 21h; Enzymatic reaction;

DOI:10.1081/SCC-100000584

Reference yield:

1-phenylethyl acetate (93-92-5,50373-55-2) + 2-heptylamine (123-82-0) → (R)-1-phenylethanol (1517-69-7) + (S)-1-phenylethyl acetate (16197-93-6) + (R)-N-(heptan-2-yl)acetamide (50789-57-6)

Guidance literature:

With hydrogen; lipase B from Candida antarctica; In toluene; at 70 ℃; for 48h; under 750.075 Torr; Resolution of racemate; Enzymatic reaction;

DOI:10.1002/ejoc.201400042

Reference yield:

1-phenylethyl acetate (93-92-5,50373-55-2) + 2-heptylamine (123-82-0) → (R)-1-phenylethanol (1517-69-7) + (R)-N-(heptan-2-yl)acetamide (50789-57-6)

Guidance literature:

With molecular sieve; lipase B from Candida antarctica; In 1,4-dioxane; at 30 ℃; Enzymatic reaction;

DOI:10.1016/S0957-4166(00)00069-0

upstream raw materials:

1-phenylethyl acetate

2-heptylamine

ethyl acetate

n-pentyl methyl ketone