5,17-Dibenzyl-2,8,14,20-tetrabutyl-11,23-dichloro-2,5,8,10,12,14,17,20,22,24,25,26-dodecaaza-tricyclo[19.3.1.1^9,13]hexacosa-1⁽²⁵⁾,9,11,13⁽²⁶⁾,21,23-hexaene

Base Information

• Chemical Name: 5,17-Dibenzyl-2,8,14,20-tetrabutyl-11,23-dichloro-2,5,8,10,12,14,17,20,22,24,25,26-dodecaaza-tricyclo[19.3.1.1^9,13]hexacosa-1⁽²⁵⁾,9,11,13⁽²⁶⁾,21,23-hexaene
• CAS No.: 91817-03-7
• Molecular Formula: C₄₄H₆₆Cl₂N₁₂
• Molecular Weight: 833.994
• Mol file: 91817-03-7.mol

Synonyms:5,17-Dibenzyl-2,8,14,20-tetrabutyl-11,23-dichloro-2,5,8,10,12,14,17,20,22,24,25,26-dodecaaza-tricyclo[19.3.1.1^9,13]hexacosa-1⁽²⁵⁾,9,11,13⁽²⁶⁾,21,23-hexaene

Chemical Property of 5,17-Dibenzyl-2,8,14,20-tetrabutyl-11,23-dichloro-2,5,8,10,12,14,17,20,22,24,25,26-dodecaaza-tricyclo[19.3.1.1^9,13]hexacosa-1⁽²⁵⁾,9,11,13⁽²⁶⁾,21,23-hexaene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,17-Dibenzyl-2,8,14,20-tetrabutyl-11,23-dichloro-2,5,8,10,12,14,17,20,22,24,25,26-dodecaaza-tricyclo[19.3.1.1^9,13]hexacosa-1⁽²⁵⁾,9,11,13⁽²⁶⁾,21,23-hexaene

There total 6 articles about 5,17-Dibenzyl-2,8,14,20-tetrabutyl-11,23-dichloro-2,5,8,10,12,14,17,20,22,24,25,26-dodecaaza-tricyclo[19.3.1.1^9,13]hexacosa-1⁽²⁵⁾,9,11,13⁽²⁶⁾,21,23-hexaene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

N-Benzyl-N'-butyl-N-(2-butylamino-ethyl)-ethane-1,2-diamine (91817-11-7) + N-Benzyl-N'-butyl-N-{2-[butyl-(4,6-dichloro-[1,3,5]triazin-2-yl)-amino]-ethyl}-N'-(4,6-dichloro-[1,3,5]triazin-2-yl)-ethane-1,2-diamine (91817-13-9) → 5,17-Dibenzyl-2,8,14,20-tetrabutyl-11,23-dichloro-2,5,8,10,12,14,17,20,22,24,25,26-dodecaaza-tricyclo[19.3.1.19,13]hexacosa-1(25),9,11,13(26),21,23-hexaene (91817-03-7)

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; water; for 15h; Heating;

DOI:10.1021/jo00196a019

Reference yield:

butanoic acid anhydride (106-31-0) → 5,17-Dibenzyl-2,8,14,20-tetrabutyl-11,23-dichloro-2,5,8,10,12,14,17,20,22,24,25,26-dodecaaza-tricyclo[19.3.1.19,13]hexacosa-1(25),9,11,13(26),21,23-hexaene (91817-03-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 93 percent / toluene / 1 h / 50 °C

2: 87 percent / LiAlH₄ / tetrahydrofuran / 40 h / Heating

3: 69 percent / anhydrous K₂CO₃ / acetone / 2 h / 0 - 5 °C

4: 59 percent / aqueous KOH / tetrahydrofuran; H₂O / 15 h / Heating

With potassium hydroxide; lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; water; acetone; toluene;

DOI:10.1021/jo00196a019

Reference yield:

N-benzyl-N,N-bis(2-phthalimidoethyl)amine (23538-88-7) → 5,17-Dibenzyl-2,8,14,20-tetrabutyl-11,23-dichloro-2,5,8,10,12,14,17,20,22,24,25,26-dodecaaza-tricyclo[19.3.1.19,13]hexacosa-1(25),9,11,13(26),21,23-hexaene (91817-03-7)

Guidance literature:

Multi-step reaction with 5 steps

1: 98 percent / hydrazin hydrate / ethanol / 3 h / Heating

2: 93 percent / toluene / 1 h / 50 °C

3: 87 percent / LiAlH₄ / tetrahydrofuran / 40 h / Heating

4: 69 percent / anhydrous K₂CO₃ / acetone / 2 h / 0 - 5 °C

5: 59 percent / aqueous KOH / tetrahydrofuran; H₂O / 15 h / Heating

With potassium hydroxide; lithium aluminium tetrahydride; potassium carbonate; hydrazine hydrate; In tetrahydrofuran; ethanol; water; acetone; toluene;

DOI:10.1021/jo00196a019

upstream raw materials:

N-Benzyl-N'-butyl-N-(2-butylamino-ethyl)-ethane-1,2-diamine

N-Benzyl-N'-butyl-N-{2-[butyl-(4,6-dichloro-[1,3,5]triazin-2-yl)-amino]-ethyl}-N'-(4,6-dichloro-[1,3,5]triazin-2-yl)-ethane-1,2-diamine

butanoic acid anhydride

N-benzyl-N,N-bis(2-phthalimidoethyl)amine