1-(benzo[b]thiophen-6-yl)-3-((5-((2-(1-methyl-1H-pyrazol-4-yl) phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)urea

Base Information

Chemical Name:1-(benzo[b]thiophen-6-yl)-3-((5-((2-(1-methyl-1H-pyrazol-4-yl) phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)urea
CAS No.:1620291-10-2
Molecular Formula:C₂₄H₂₃N₅O₃S
Molecular Weight:461.544
Hs Code.:

Synonyms:1-(benzo[b]thiophen-6-yl)-3-((5-((2-(1-methyl-1H-pyrazol-4-yl) phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)urea

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Chemical Property of 1-(benzo[b]thiophen-6-yl)-3-((5-((2-(1-methyl-1H-pyrazol-4-yl) phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)urea

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Technology Process of 1-(benzo[b]thiophen-6-yl)-3-((5-((2-(1-methyl-1H-pyrazol-4-yl) phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)urea

There total 2 articles about 1-(benzo[b]thiophen-6-yl)-3-((5-((2-(1-methyl-1H-pyrazol-4-yl) phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1620293-11-9
(5-((2-(1-methyl-1H-pyrazol-4-yl)phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methanamine hydrochloride

: 1620293-25-5
phenyl benzo[b]thiophen-6-ylcarbamate

: 1620291-10-2
1-(benzo[b]thiophen-6-yl)-3-((5-((2-(1-methyl-1H-pyrazol-4-yl) phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)urea

Guidance literature:: With triethylamine; In dimethyl sulfoxide; at 20 ℃; for 16h; Inert atmosphere;

Reference yield:

: 1620293-23-3
benzo[b]thiophen-6-amine hydrochloride

: 1620291-10-2
1-(benzo[b]thiophen-6-yl)-3-((5-((2-(1-methyl-1H-pyrazol-4-yl) phenoxy)methyl)-4,5-dihydroisoxazol-3-yl)methyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / acetonitrile; tetrahydrofuran / 2 h / 0 °C

2: triethylamine / dimethyl sulfoxide / 16 h / 20 °C / Inert atmosphere

With pyridine; triethylamine; In tetrahydrofuran; dimethyl sulfoxide; acetonitrile;