2-Amino-1-(pyridin-3-yl)ethanone hydrochloride

Base Information

• Chemical Name: 2-Amino-1-(pyridin-3-yl)ethanone hydrochloride
• CAS No.: 93103-00-5
• Molecular Formula: C7H8 N2 O . Cl H
• Molecular Weight: 172.614
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID30535012
• Mol file: 93103-00-5.mol

Synonyms:93103-00-5;2-Amino-1-(pyridin-3-yl)ethanone hydrochloride;2-amino-1-pyridin-3-ylethanone;hydrochloride;2-Amino-1-(pyridin-3-yl)ethanone HCl;2-amino-1-(pyridin-3-yl)ethan-1-one hydrochloride;Ethanone, 2-amino-1-(3-pyridinyl)-, monohydrochloride;2-AMINO-1-PYRIDIN-3-YL-ETHANONE HYDROCHLORIDE;SCHEMBL5419648;DTXSID30535012;NZRHWLYBXKDQFN-UHFFFAOYSA-N;MFCD03093361;SB54673;SY354628;2-Amino-1-(pyridin-3-yl)ethanonehydrochloride;F13353;2-Amino-1-(pyridin-3-yl)ethan-1-one--hydrogen chloride (1/1)

Chemical Property of 2-Amino-1-(pyridin-3-yl)ethanone hydrochloride

Chemical Property:

• PSA: 55.98000
• LogP: 1.72530
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 172.0403406
• Heavy Atom Count: 11
• Complexity: 125

Purity/Quality:

98%Min ^*data from raw suppliers

2-amino-1-pyridin-3-yl-ethanonehydrochloride 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CN=C1)C(=O)CN.Cl

Technology Process of 2-Amino-1-(pyridin-3-yl)ethanone hydrochloride

There total 14 articles about 2-Amino-1-(pyridin-3-yl)ethanone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyl (2-oxo-2-(pyridin-3-yl)ethyl)carbamate (473693-42-4) → 2-amino-1-pyridin-3-yl-ethanone dihydrochloride salt (51746-82-8,93103-00-5)

Guidance literature:

With hydrogenchloride; In methanol; isopropyl alcohol; at 50 ℃; for 2h;

Reference yield: 85.0%

1-pyridin-3-yl-ethanone oxime O-tosylate (74209-51-1) → 2-amino-1-pyridin-3-yl-ethanone dihydrochloride salt (51746-82-8,93103-00-5)

Guidance literature:

1-pyridin-3-yl-ethanone oxime O-tosylate; With potassium tert-butylate; In methanol; at 10 - 25 ℃; for 2h;

With hydrogenchloride; In water; at 80 ℃; for 3h; Reagent/catalyst; Time; Temperature;

Reference yield: 81.0%

N-formyl-N-(2-oxo-2-(pyridin-3-yl)ethyl)formamide → 2-amino-1-(pyridin-3-yl)ethanone hydrochloride (93103-00-5)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 50 ℃;

upstream raw materials:

2-hydroxyimino-3-oxo-3-[3]pyridyl-propionic acid ethyl ester

2-hydroxyimino-1-(3-pyridyl)-1-ethanone

methyl-3-pyridylketone

3-oxo-3-pyridin-3-yl-propionic acid ethyl ester

Downstream raw materials:

2-amino-1-(pyridine-3-yl)ethanol

4-(pyridin-3-yl)-1H-imidazole-2(3H)-thione

3-(1H-imidazol-4-yl)pyridine

N-cyclohexyl-N-methyl-4-(pyridin-3-yl)-1H-imidazole-1-carboxamide