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3-Acetylpyridine

Base Information Edit
  • Chemical Name:3-Acetylpyridine
  • CAS No.:350-03-8
  • Molecular Formula:C7H7NO
  • Molecular Weight:121.139
  • Hs Code.:2933.39
  • European Community (EC) Number:206-496-7
  • NSC Number:761
  • UNII:00QT8FX306
  • DSSTox Substance ID:DTXSID7044421
  • Nikkaji Number:J5.689H
  • Wikidata:Q27231372
  • Metabolomics Workbench ID:45902
  • ChEMBL ID:CHEMBL3187172
  • Mol file:350-03-8.mol
3-Acetylpyridine

Synonyms:1-pyridin-3-yl-ethanone;3-acetylpyridine

Suppliers and Price of 3-Acetylpyridine
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 3-Acetylpyridine
  • 250g
  • $ 240.00
  • TCI Chemical
  • 3-Acetylpyridine >98.0%(GC)
  • 25g
  • $ 43.00
  • TCI Chemical
  • 3-Acetylpyridine >98.0%(GC)
  • 250g
  • $ 229.00
  • SynQuest Laboratories
  • 3-Acetylpyridine 97%
  • 500 g
  • $ 304.00
  • SynQuest Laboratories
  • 3-Acetylpyridine 97%
  • 100 g
  • $ 136.00
  • Sigma-Aldrich
  • 3-Acetylpyridine 98%
  • 100g
  • $ 65.00
  • Sigma-Aldrich
  • 3-Acetylpyridine ≥98%,FG
  • 1 SAMPLE-K
  • $ 50.00
  • Sigma-Aldrich
  • 3-Acetylpyridine ≥98%, FG
  • sample-k
  • $ 50.00
  • Sigma-Aldrich
  • 3-Acetylpyridine ≥98%, FG
  • 100 g
  • $ 106.00
  • Sigma-Aldrich
  • 3-Acetylpyridine ≥98%, FG
  • 100g-k
  • $ 106.00
Total 213 raw suppliers
Chemical Property of 3-Acetylpyridine Edit
Chemical Property:
  • Appearance/Colour:clear colorless to yellow liquid 
  • Vapor Pressure:0.111mmHg at 25°C 
  • Melting Point:11-13 °C(lit.) 
  • Refractive Index:n20/D 1.534(lit.)  
  • Boiling Point:220.8 °C at 760 mmHg 
  • PKA:pK1: 3.256(+1) (25°C) 
  • Flash Point:92.3 °C 
  • PSA:29.96000 
  • Density:1.06 g/cm3 
  • LogP:1.28420 
  • Storage Temp.:Refrigerator 
  • Water Solubility.:SOLUBLE IN HOT WATER 
  • XLogP3:0.4
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:1
  • Exact Mass:121.052763847
  • Heavy Atom Count:9
  • Complexity:112
Purity/Quality:

99% *data from raw suppliers

3-Acetylpyridine *data from reagent suppliers

Safty Information:
  • Pictogram(s): ToxicT, IrritantXi, HarmfulXn 
  • Hazard Codes:T,Xi,Xn 
  • Statements: 25-36/38-36/37/38-20/21/22 
  • Safety Statements: 45-37/39-28A-26-36 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(=O)C1=CN=CC=C1
  • Description A colorless liquid with sweet, nutty, popcorn-like aroma.
  • Uses 3-Acetylpyridine used as an intermediate for the synthesis of risedronate sodium, inhibitor of bone resorption. It is also used in perfumery. Used in the fragrance industry and as an intermediate in the synthesis of a number of clinical drugs, including Imatinib, Mesylate, Metyrapone, Telithromycin, and Ridogrel. An analog of nicotinamide that competes for incorporation into NAD. It has been used to chemically lesion the inferior olive nucleus, thereby eliminating climbing fibers within the cerebellar cortex.
Technology Process of 3-Acetylpyridine

There total 74 articles about 3-Acetylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With (4,4′-di-tert-butyl-2,2′-bipyridine)bis[(2-pyridinyl)phenyl]iridium(III) hexafluorophosphate; di-tert-butyl 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylate; In acetonitrile; at 20 ℃; for 0.5h; chemoselective reaction; Inert atmosphere; Irradiation;
DOI:10.1021/acs.joc.0c02805
Guidance literature:
With sulfuric acid; dihydrogen peroxide; sodium bromide; In 1,4-dioxane; water; at 70 ℃; Flow reactor; Green chemistry;
DOI:10.1016/j.tetlet.2015.07.069
Guidance literature:
With tert.-butylhydroperoxide; In ethylbenzene; water; at 135 ℃; for 24h; Concentration; Temperature; Time; Sealed tube;
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