benzyl endo-7-chlorobicyclo[4.1.0]heptane-7-carboxylate

Base Information

• Chemical Name: benzyl endo-7-chlorobicyclo[4.1.0]heptane-7-carboxylate
• CAS No.: 1091681-85-4
• Molecular Formula: C₁₅H₁₇ClO₂
• Molecular Weight: 264.752
• Mol file: 1091681-85-4.mol

Synonyms:benzyl endo-7-chlorobicyclo[4.1.0]heptane-7-carboxylate

Chemical Property of benzyl endo-7-chlorobicyclo[4.1.0]heptane-7-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl endo-7-chlorobicyclo[4.1.0]heptane-7-carboxylate

There total 1 articles about benzyl endo-7-chlorobicyclo[4.1.0]heptane-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

endo-7-Chlor-exo-7-carboxynorcaran (18688-20-5) + benzyl bromide (100-39-0) → benzyl endo-7-chlorobicyclo[4.1.0]heptane-7-carboxylate (1091681-85-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 5 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol8022038

Reference yield: 79.0%

benzyl endo-7-chlorobicyclo[4.1.0]heptane-7-carboxylate (1091681-85-4) + pentan-3-one (96-22-0) → benzyl endo-7-(1-ethyl-1-hydroxypropyl)bicyclo[4.1.0]heptane-7-carboxylate (1092493-30-5)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; samarium diiodide; In tetrahydrofuran; at 20 ℃; for 2h; stereoselective reaction; Inert atmosphere;

DOI:10.1021/ol8022038

upstream raw materials:

endo-7-Chlor-exo-7-carboxynorcaran

benzyl bromide

Downstream raw materials:

benzyl endo-7-(1-ethyl-1-hydroxypropyl)bicyclo[4.1.0]heptane-7-carboxylate