(2-Hydroxymethyl-phenoxy)-acetic acid

Base Information

Chemical Name:(2-Hydroxymethyl-phenoxy)-acetic acid
CAS No.:97388-49-3
Molecular Formula:C9H10 O4
Molecular Weight:182.17
Hs Code.:2918990090
NSC Number:171103
DSSTox Substance ID:DTXSID70305559
Wikidata:Q82052222
Mol file:97388-49-3.mol

Synonyms:2-(2-(Hydroxymethyl)phenoxy)acetic acid;97388-49-3;(2-Hydroxymethyl-phenoxy)-acetic acid;2-[2-(hydroxymethyl)phenoxy]acetic acid;NSC171103;2-Carboxymethoxybenzylalcohol;SCHEMBL3409855;DTXSID70305559;KTFBOHKOJFLUKP-UHFFFAOYSA-N;XDA38849;MFCD06202610;AKOS012964031;NSC-171103;2-(2-(Hydroxymethyl)phenoxy)aceticacid;4?-piperidinocarbonylmethoxy-acetophenon;BS-18000;CS-0156638;C77342

Suppliers and Price of (2-Hydroxymethyl-phenoxy)-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(2-(Hydroxymethyl)phenoxy)aceticacid 97%
1g
$ 317.00

AK Scientific
(2-Hydroxymethyl-phenoxy)-aceticacid
1g
$ 243.00

AK Scientific
(2-Hydroxymethyl-phenoxy)-aceticacid
250mg
$ 134.00

AK Scientific
(2-Hydroxymethyl-phenoxy)-aceticacid
100mg
$ 108.00

Total 6 raw suppliers

Chemical Property of (2-Hydroxymethyl-phenoxy)-acetic acid

Chemical Property:

Melting Point:129-130 °C(Solv: ethyl acetate (141-78-6))
Boiling Point:362.1±22.0 °C(Predicted)
PKA:3.16±0.10(Predicted)
PSA：66.76000
Density:1.316±0.06 g/cm3(Predicted)
LogP:0.64230
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:182.05790880
Heavy Atom Count:13
Complexity:169

Purity/Quality:

99% ^*data from raw suppliers

2-(2-(Hydroxymethyl)phenoxy)aceticacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CO)OCC(=O)O

Technology Process of (2-Hydroxymethyl-phenoxy)-acetic acid

There total 6 articles about (2-Hydroxymethyl-phenoxy)-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 111080-48-9
ethyl 2-[2-(hydroxymethyl)phenoxy]acetate

: 97388-49-3
(2-hydroxymethyl-phenoxy)-acetic acid

Guidance literature:: With sodium hydroxide; water; In methanol;
DOI:10.1016/j.bmc.2008.10.011

Reference yield:

: 90-01-7
salicylic alcohol

: 79-11-8
chloroacetic acid

: 97388-49-3
(2-hydroxymethyl-phenoxy)-acetic acid

Guidance literature:: With sodium hydroxide; at 108 - 110 ℃;

Reference yield:

: 90-02-8
salicylaldehyde

: 97388-49-3
(2-hydroxymethyl-phenoxy)-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: (i) NaOMe, MeOH, (ii) /BRN= 506256/

2: KOH / methanol

3: NaBH₄, aq. NaOH

With potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; In methanol;
DOI:10.1021/jm00303a018