C₁₈H₂₈O₄

Base Information

• Chemical Name: C₁₈H₂₈O₄
• CAS No.: 1343505-16-7
• Molecular Formula: C₁₈H₂₈O₄
• Molecular Weight: 308.418
• Mol file: 1343505-16-7.mol

Synonyms:C₁₈H₂₈O₄

Chemical Property of C₁₈H₂₈O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₈H₂₈O₄

There total 1 articles about C₁₈H₂₈O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C18H30O4 (1343505-09-8) → C18H28O4 (1343505-16-7)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; at -10 ℃; for 2h; Molecular sieve;

DOI:10.1016/j.tetlet.2011.08.158

Reference yield: 96.0%

C18H28O4 (1343505-16-7) + tert-butyldimethylsilyl chloride (18162-48-6) → C24H42O4Si (1343505-20-3)

Guidance literature:

With 2,6-dimethylpyridine; In dichloromethane; at 20 ℃; for 0.75h;

DOI:10.1016/j.tetlet.2011.08.158

Reference yield:

C18H28O4 (1343505-16-7) → C46H66N2O7Si (1343505-22-5)

Guidance literature:

Multi-step reaction with 5 steps

1: 2,6-dimethylpyridine / dichloromethane / 0.75 h / 20 °C

2: diisobutylaluminium hydride / dichloromethane / 2 h / -40 - -10 °C

3: Dess-Martin periodane / dichloromethane / 1 h / 0 - 20 °C

4: sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene / water; tert-butyl alcohol / 1 h

5: 1-ethyl-piperidine; HATU / acetonitrile / 12 h / 0 - 20 °C

With 1-ethyl-piperidine; 2,6-dimethylpyridine; sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; diisobutylaluminium hydride; Dess-Martin periodane; HATU; In dichloromethane; water; acetonitrile; tert-butyl alcohol;

DOI:10.1016/j.tetlet.2011.08.158

upstream raw materials:

C₁₈H₃₀O₄

Downstream raw materials:

C₂₄H₄₄O₄Si

C₂₄H₄₂O₅Si

C₄₆H₆₆N₂O₇Si

C₄₀H₅₂N₂O₇