N⁶-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-(2,5-dichlorophenyl 2-cyanoethyl phosphate)

Base Information

• Chemical Name: N⁶-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-(2,5-dichlorophenyl 2-cyanoethyl phosphate)
• CAS No.: 132849-81-1
• Molecular Formula: C₅₂H₅₃Cl₂N₆O₉PSi
• Molecular Weight: 1035.99

Synonyms:N⁶-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-(2,5-dichlorophenyl 2-cyanoethyl phosphate)

Chemical Property of N⁶-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-(2,5-dichlorophenyl 2-cyanoethyl phosphate)

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N⁶-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-(2,5-dichlorophenyl 2-cyanoethyl phosphate)

There total 3 articles about N⁶-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-(2,5-dichlorophenyl 2-cyanoethyl phosphate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dichlorophenyl phosphorodichloridate (53676-18-9) → N6-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-(2,5-dichlorophenyl 2-cyanoethyl phosphate) (132849-81-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,2,4-triazole, pyridine / 30 h / 0 °C

2: 1,2,4-triazole, pyridine / 12 h / Ambient temperature

With pyridine; 1,2,4-Triazole;

DOI:10.1002/hlca.19910740104

Reference yield:

N6-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine (69504-10-5) → N6-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-(2,5-dichlorophenyl 2-cyanoethyl phosphate) (132849-81-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,2,4-triazole, pyridine / 30 h / 0 °C

2: 1,2,4-triazole, pyridine / 12 h / Ambient temperature

With pyridine; 1,2,4-Triazole;

DOI:10.1002/hlca.19910740104

Reference yield:

Phosphorochloridic acid (2R,3R,4R,5R)-2-(6-benzoylamino-purin-9-yl)-4-(tert-butyl-dimethyl-silanyloxy)-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-3-yl ester 2,5-dichloro-phenyl ester + 3-Hydroxypropionitrile (109-78-4) → N6-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-(2,5-dichlorophenyl 2-cyanoethyl phosphate) (132849-81-1)

Guidance literature:

With pyridine; 1,2,4-Triazole; for 12h; Yield given; Ambient temperature;

DOI:10.1002/hlca.19910740104

upstream raw materials:

3-Hydroxypropionitrile

2,5-dichlorophenyl phosphorodichloridate

N⁶-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine

Downstream raw materials:

N⁶-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-(2,5-dichlorophenyl triethylammonium phosphate)

N⁶-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>adenosine 2'-(2,5-dichlorophenyl 2-cyanoethyl phosphate)

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 132849-81-1 N⁶-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-(2,5-dichlorophenyl 2-cyanoethyl phosphate)

Send

Send

Metric Ton KG G Pound L ML

Send

Send