2,5-Dichlorophenyl dichlorophosphate

Base Information

• Chemical Name: 2,5-Dichlorophenyl dichlorophosphate
• CAS No.: 53676-18-9
• Molecular Formula: C6H3 Cl4 O2 P
• Molecular Weight: 279.874
• Hs Code.: 2931900090
• European Community (EC) Number: 258-694-8
• DSSTox Substance ID: DTXSID20201916
• Nikkaji Number: J296.012E
• Wikidata: Q83075148
• Mol file: 53676-18-9.mol

Synonyms:2,5-Dichlorophenyl dichlorophosphate;53676-18-9;2,5-Dichlorophenyl phosphorodichloridate;1,4-dichloro-2-dichlorophosphoryloxybenzene;EINECS 258-694-8;starbld0005209;C6H3Cl4O2P;SCHEMBL2987764;C6-H3-Cl4-O2-P;DTXSID20201916;(2,5-dichlorophenoxy)phosphonoyl dichloride;FT-0610324;Dichloridophosphoric acid 2,5-dichlorophenyl ester

Chemical Property of 2,5-Dichlorophenyl dichlorophosphate

Chemical Property:

• Vapor Pressure: 0.00364mmHg at 25°C
• Melting Point: 36-38 °C(lit.)
• Boiling Point: 141 °C9 mm Hg(lit.)
• Flash Point: 161.5°C
• PSA: 36.11000
• Density: 1.668g/cm³
• LogP: 4.95790
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 279.859527
• Heavy Atom Count: 13
• Complexity: 219

Purity/Quality:

98%Min ^*data from raw suppliers

2,5-DICHLOROPHENYL DICHLOROPHOSPHATE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34-37
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)OP(=O)(Cl)Cl)Cl

Technology Process of 2,5-Dichlorophenyl dichlorophosphate

There total 2 articles about 2,5-Dichlorophenyl dichlorophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dichlorophenol (583-78-8) → 2,5-dichlorophenyl phosphorodichloridate (53676-18-9)

Guidance literature:

With pyridine; trichlorophosphate;

Reference yield:

→ 2,5-dichlorophenyl phosphorodichloridate (53676-18-9)

Guidance literature:

/BRN= 906458/, POCl3, Ether, Pyridin;

Reference yield: 94.0%

2,2-diphenyl ethanol (1883-32-5) + 2,5-dichlorophenyl phosphorodichloridate (53676-18-9) + 5'-O-(4-monomethoxytrityl)-2'-deoxythymidine (42926-80-7) → 5'-O-(monomethoxytrityl)thymidine 3'-(2,5-dichlorophenyl 2,2-diphenylethyl phosphate) (322732-68-3)

Guidance literature:

2,5-dichlorophenyl phosphorodichloridate; With 1,2,4-Triazole; In pyridine; at 0 ℃; for 0.5h;

5'-O-(4-monomethoxytrityl)-2'-deoxythymidine; In pyridine; for 1h;

2,2-diphenyl ethanol; In pyridine; for 24h;

DOI:10.1002/1522-2675(20001108)83:11<3053::AID-HLCA3053>3.0.CO;2-X

upstream raw materials:

2,5-dichlorophenol

Downstream raw materials:

phosphoric acid diallyl ester-(2,5-dichloro-phenyl ester)

2,5-dichlorophenyl phosphate

N²-Isobutyryl-5'-O-dimethoxytrityl-2'-deoxyguanosine-3' 2,5-dichlorophenyl 2-(4-nitrophenyl)-ethyl phosphate

N⁶-benzoyl-3'-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenosine 2'-<2,5-dichlorophenyl 2-(4-nitrophenyl)ethyl phosphate>

Refernces