1-[3-(tert-butyldimethylsilyloxymethyl)-phenyl]-1-phenylethylene

Base Information

• Chemical Name: 1-[3-(tert-butyldimethylsilyloxymethyl)-phenyl]-1-phenylethylene
• CAS No.: 853944-39-5
• Molecular Formula: C₂₁H₂₈OSi
• Molecular Weight: 324.538
• Mol file: 853944-39-5.mol

Synonyms:1-[3-(tert-butyldimethylsilyloxymethyl)-phenyl]-1-phenylethylene

Chemical Property of 1-[3-(tert-butyldimethylsilyloxymethyl)-phenyl]-1-phenylethylene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[3-(tert-butyldimethylsilyloxymethyl)-phenyl]-1-phenylethylene

There total 5 articles about 1-[3-(tert-butyldimethylsilyloxymethyl)-phenyl]-1-phenylethylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3-(1-phenylvinyl)benzyl alcohol (85366-49-0) + tert-butyldimethylsilyl chloride (18162-48-6) → 1-[3-(tert-butyldimethylsilyloxymethyl)-phenyl]-1-phenylethylene (853944-39-5)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 25 ℃; for 6h;

DOI:10.1021/ma050248e

Reference yield:

1-(3-formylphenyl)-1-phenylethanol (86888-84-8) → 1-[3-(tert-butyldimethylsilyloxymethyl)-phenyl]-1-phenylethylene (853944-39-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 77 percent / p-toluenesulfonic acid / benzene / 3 h / 70 °C

2: 96 percent / NaBH₄ / ethanol / 12 h / 25 °C

3: 88 percent / imidazole / dimethylformamide / 6 h / 25 °C

With 1H-imidazole; sodium tetrahydroborate; toluene-4-sulfonic acid; In ethanol; N,N-dimethyl-formamide; benzene;

DOI:10.1021/ma050248e

Reference yield:

1-(3-formylphenyl)-1-phenylethylene (85366-55-8) → 1-[3-(tert-butyldimethylsilyloxymethyl)-phenyl]-1-phenylethylene (853944-39-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / NaBH₄ / ethanol / 12 h / 25 °C

2: 88 percent / imidazole / dimethylformamide / 6 h / 25 °C

With 1H-imidazole; sodium tetrahydroborate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1021/ma050248e

upstream raw materials:

3-(1-phenylvinyl)benzyl alcohol

tert-butyldimethylsilyl chloride

1-(3-formylphenyl)-1-phenylethanol

1-(3-formylphenyl)-1-phenylethylene