(1-biphenyl-4-yl-1H-[1,2,3]triazol-4-yl)methanol

Base Information

• Chemical Name: (1-biphenyl-4-yl-1H-[1,2,3]triazol-4-yl)methanol
• CAS No.: 1258941-52-4
• Molecular Formula: C₁₅H₁₃N₃O
• Molecular Weight: 251.288
• Mol file: 1258941-52-4.mol

Synonyms:(1-biphenyl-4-yl-1H-[1,2,3]triazol-4-yl)methanol

Chemical Property of (1-biphenyl-4-yl-1H-[1,2,3]triazol-4-yl)methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1-biphenyl-4-yl-1H-[1,2,3]triazol-4-yl)methanol

There total 1 articles about (1-biphenyl-4-yl-1H-[1,2,3]triazol-4-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

4-bromo-1,1'-biphenyl (92-66-0) + propargyl alcohol (107-19-7) → (1-biphenyl-4-yl-1H-[1,2,3]triazol-4-yl)methanol (1258941-52-4)

Guidance literature:

4-bromo-1,1'-biphenyl; With copper(l) iodide; sodium azide; sodium L-ascorbate; N,N`-dimethylethylenediamine; In ethanol; water; at 20 ℃; Inert atmosphere; Reflux;

propargyl alcohol; In ethanol; water; Inert atmosphere; Reflux;

DOI:10.1039/b9nj00785g

Reference yield: 27.0%

tetrakis(2-phenylpyridinato-N,C2)(μ-dihydroxy)diiridium(III) + (1-biphenyl-4-yl-1H-[1,2,3]triazol-4-yl)methanol (1258941-52-4) → bis(2-phenylpyridinato-N,C2)((1-biphenyl-4-yl-1H-[1,2,3]triazol-4-yl)carboxylate-N3,O)iridium(III) (1258941-53-5)

Guidance literature:

In chloroform; Ir complex and ligand in CHCl3 sealed; degassed with Ar at room temp. for 30 min; heated to 70°C for 12 h with stirring; cooled to room temp.; added dropwise into n-pentane; filtered; ppt. washed with n-pentane; dissolved in CH2Cl2; washed with H2O; dried (MgSO4); concd. CH2Cl2 phase poured into n-pentane; ppt. purified by column chromy. (Al2O3, CH2Cl2-MeOH98:2); elem. anal.;

DOI:10.1039/b9nj00785g

upstream raw materials:

4-bromo-1,1'-biphenyl

propargyl alcohol

Downstream raw materials:

bis(2-phenylpyridinato-N,C₂)((1-biphenyl-4-yl-1H-[1,2,3]triazol-4-yl)carboxylate-N₃,O)iridium(III)