Technology Process of methyl 3-O-benzyl-5-deoxy-1,2-O-isopropylidene-5-(methoxycarbonylamino)-α-D-gluco-hexofuranuronate
There total 16 articles about methyl 3-O-benzyl-5-deoxy-1,2-O-isopropylidene-5-(methoxycarbonylamino)-α-D-gluco-hexofuranuronate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 1h;
Inert atmosphere;
DOI:10.1016/j.tetasy.2011.02.004
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: methanol / 6.5 h / 20 °C / Inert atmosphere
2.1: mesitylenecarbonitrile oxide / acetonitrile / 3 h / 20 °C / Inert atmosphere
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.67 h / 0 - 20 °C / Inert atmosphere
4.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
4.2: 1.5 h / 0 - 20 °C / Inert atmosphere
5.1: sodium periodate; rhodium(III) chloride hydrate; water / tetrachloromethane; acetonitrile / 6 h / 20 °C
6.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere
With
sodium periodate; rhodium(III) chloride hydrate; tetrabutyl ammonium fluoride; water; sodium hydride; potassium carbonate; mesitylenecarbonitrile oxide;
In
tetrahydrofuran; methanol; tetrachloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.tetasy.2011.02.004
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: n-heptane / 24 h / 90 °C / Inert atmosphere
2.1: methanol / 6.5 h / 20 °C / Inert atmosphere
3.1: mesitylenecarbonitrile oxide / acetonitrile / 3 h / 20 °C / Inert atmosphere
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.67 h / 0 - 20 °C / Inert atmosphere
5.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 °C / Inert atmosphere
5.2: 1.5 h / 0 - 20 °C / Inert atmosphere
6.1: sodium periodate; rhodium(III) chloride hydrate; water / tetrachloromethane; acetonitrile / 6 h / 20 °C
7.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere
With
sodium periodate; rhodium(III) chloride hydrate; tetrabutyl ammonium fluoride; water; sodium hydride; potassium carbonate; mesitylenecarbonitrile oxide;
In
tetrahydrofuran; methanol; tetrachloromethane; n-heptane; N,N-dimethyl-formamide; acetonitrile;
1.1: aza-Claisen rearrangement;
DOI:10.1016/j.tetasy.2011.02.004
