(3R,4S)-3-Chloromethyl-4-dibenzylamino-3-hydroxy-pentanoic acid ethyl ester

Base Information

Chemical Name:(3R,4S)-3-Chloromethyl-4-dibenzylamino-3-hydroxy-pentanoic acid ethyl ester
CAS No.:426263-10-7
Molecular Formula:C₂₂H₂₈ClNO₃
Molecular Weight:389.922
Hs Code.:

Synonyms:(3R,4S)-3-Chloromethyl-4-dibenzylamino-3-hydroxy-pentanoic acid ethyl ester

Suppliers and Price of (3R,4S)-3-Chloromethyl-4-dibenzylamino-3-hydroxy-pentanoic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,4S)-3-Chloromethyl-4-dibenzylamino-3-hydroxy-pentanoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,4S)-3-Chloromethyl-4-dibenzylamino-3-hydroxy-pentanoic acid ethyl ester

There total 1 articles about (3R,4S)-3-Chloromethyl-4-dibenzylamino-3-hydroxy-pentanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 141-78-6
ethyl acetate

: 1-chloro-3-dibenzylamino-butan-2-one

: 426263-10-7
(3R,4S)-3-Chloromethyl-4-dibenzylamino-3-hydroxy-pentanoic acid ethyl ester

Guidance literature:: ethyl acetate; With lithium diisopropyl amide; In tetrahydrofuran; at -85 ℃; for 0.25h;

1-chloro-3-dibenzylamino-butan-2-one; In tetrahydrofuran; at -78 ℃; for 1h; Further stages.;
DOI:10.1021/ol025590f

Reference yield:

: 426263-10-7
(3R,4S)-3-Chloromethyl-4-dibenzylamino-3-hydroxy-pentanoic acid ethyl ester

: (+)-(2S,3S)-1-benzyl-3-ethoxycarbonylmethyl-2-methylazetidin-3-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 20 °C

2: 100 percent / HCO₂H / Pd/C / methanol / Heating

With formic acid; palladium on activated charcoal; In methanol;
DOI:10.1021/ol025590f