Ethyl 4-(tert-Butyldiphenylsiloxy)-5-methyl-hexa-2(E),5-dienoate

Base Information

• Chemical Name: Ethyl 4-(tert-Butyldiphenylsiloxy)-5-methyl-hexa-2(E),5-dienoate
• CAS No.: 97971-48-7
• Molecular Formula: C₂₅H₃₂O₃Si
• Molecular Weight: 408.613
• Mol file: 97971-48-7.mol

Synonyms:Ethyl 4-(tert-Butyldiphenylsiloxy)-5-methyl-hexa-2(E),5-dienoate

Chemical Property of Ethyl 4-(tert-Butyldiphenylsiloxy)-5-methyl-hexa-2(E),5-dienoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethyl 4-(tert-Butyldiphenylsiloxy)-5-methyl-hexa-2(E),5-dienoate

There total 9 articles about Ethyl 4-(tert-Butyldiphenylsiloxy)-5-methyl-hexa-2(E),5-dienoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

diethoxyphosphoryl-acetic acid ethyl ester (867-13-0) + 2-(tert-Butyldiphenylsiloxy)-3-methyl-but-3-enal (97971-47-6) → Ethyl 4-(tert-Butyldiphenylsiloxy)-5-methyl-hexa-2(E),5-dienoate (97971-48-7)

Guidance literature:

With sodium hydride; In benzene;

DOI:10.1248/cpb.33.1313

Reference yield:

3-(tert-Butyldiphenylsiloxy)-4-methyl-but-4-ene-1,2-diol (97971-46-5) → Ethyl 4-(tert-Butyldiphenylsiloxy)-5-methyl-hexa-2(E),5-dienoate (97971-48-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / periodic acid

2: 90 percent / sodium hydride / benzene

With sodium hydride; periodic acid; In benzene;

DOI:10.1248/cpb.33.1313

Reference yield:

4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene (97971-45-4) → Ethyl 4-(tert-Butyldiphenylsiloxy)-5-methyl-hexa-2(E),5-dienoate (97971-48-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 90 percent / trifluoroacetic acid / methanol

2: 95 percent / periodic acid

3: 90 percent / sodium hydride / benzene

With sodium hydride; periodic acid; trifluoroacetic acid; In methanol; benzene;

DOI:10.1248/cpb.33.1313

upstream raw materials:

diethoxyphosphoryl-acetic acid ethyl ester

2-(tert-Butyldiphenylsiloxy)-3-methyl-but-3-enal

3-(tert-Butyldiphenylsiloxy)-4-methyl-but-4-ene-1,2-diol

4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene

Downstream raw materials:

Ethyl 4(R)-(tert-Butyldiphenylsiloxy)-5,6-epoxy-5(S)-methyl-but-2(E)-enoate

Ethyl 4(R)-(tert-Butyldiphenylsiloxy)-5,6-epoxy-5(R)-methyl-but-2(E)-enoate