4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene

Base Information

• Chemical Name: 4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene
• CAS No.: 97971-45-4
• Molecular Formula: C₂₅H₃₄O₃Si
• Molecular Weight: 410.629
• Mol file: 97971-45-4.mol

Synonyms:4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene

Chemical Property of 4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene

There total 10 articles about 4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpentan-2-ol (130258-74-1) → 4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene (97971-45-4)

Guidance literature:

With pyridine; thionyl chloride; for 1h; Ambient temperature;

DOI:10.1248/cpb.38.1451

Reference yield:

Kalium-<4S-(R*,S*)>-α-hydroxy-2,2-dimethyl-1,3-dioxolan-4-acetat (93367-08-9) → 4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene (97971-45-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 63 percent / HCl / methanol / -78 °C

4: 80 percent / thionyl chloride / pyridine

With hydrogenchloride; thionyl chloride; In pyridine; methanol;

DOI:10.1248/cpb.33.1313

Reference yield:

methyl (2R,3S)-3,4-O-isopropylidene-2,3,4-trihydroxybutanoate (92973-40-5) → 4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpent-1-ene (97971-45-4)

Guidance literature:

Multi-step reaction with 4 steps

3: 80 percent / thionyl chloride / pyridine

With thionyl chloride; In pyridine;

DOI:10.1248/cpb.33.1313

upstream raw materials:

4,5-Isopropylidenedioxy-3-(tert-butyldiphenylsiloxy)-2-methylpentan-2-ol

Benzoic acid (S)-1-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-allyl ester

Kalium-<4S-(R*,S*)>-α-hydroxy-2,2-dimethyl-1,3-dioxolan-4-acetat

(R)-1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-methyl-propane-1,2-diol

Downstream raw materials:

3-(tert-Butyldiphenylsiloxy)-4-methyl-but-4-ene-1,2-diol

Methyl 8(R)-(tert-Butyldiphenylsiloxy)-9,10-epoxy-9(R)-methyldeca-2(E),4(E),6(E)-trienoate

Methyl 8(R)-(tert-Butyldiphenylsiloxy)-9,10 epoxy-9(R)-methyldeca-2(E),4(Z),6(E)-trienoate

Methyl 8(R)-(tert-Butyldiphenylsiloxy)-9,10-epoxy-9(S)-methyldeca-2(E),4(E),6(E)-trienoate