2-{5-[3-(5-fluoro-2-methoxyphenyl)ethyl]tetrahydro-furan-2-yl}ethylamine

Base Information

Chemical Name:2-{5-[3-(5-fluoro-2-methoxyphenyl)ethyl]tetrahydro-furan-2-yl}ethylamine
CAS No.:878661-48-4
Molecular Formula:C₁₅H₂₂FNO₂
Molecular Weight:267.344
Hs Code.:

Synonyms:2-{5-[3-(5-fluoro-2-methoxyphenyl)ethyl]tetrahydro-furan-2-yl}ethylamine

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Chemical Property of 2-{5-[3-(5-fluoro-2-methoxyphenyl)ethyl]tetrahydro-furan-2-yl}ethylamine

Chemical Property:

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Technology Process of 2-{5-[3-(5-fluoro-2-methoxyphenyl)ethyl]tetrahydro-furan-2-yl}ethylamine

There total 1 articles about 2-{5-[3-(5-fluoro-2-methoxyphenyl)ethyl]tetrahydro-furan-2-yl}ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: trans-2-(cyanomethyl)-5-(2'-methoxy-5'-fluorophenethyl)tetrahydrofuran

: 878661-48-4
2-{5-[3-(5-fluoro-2-methoxyphenyl)ethyl]tetrahydro-furan-2-yl}ethylamine

: N,N-bis(5'-(5''-fluoro-2''-methoxyphenethyl)-2'-tetrahydrofurylethyl)amine

Guidance literature:: With hydrogen; In ethanol; at 20 ℃; for 96h;

Reference yield: 31.0%

: 878661-48-4
2-{5-[3-(5-fluoro-2-methoxyphenyl)ethyl]tetrahydro-furan-2-yl}ethylamine

: 2-(5-bromo-pentyl)-4-(3,4-dimethoxy-phenyl)-4a,5,8,8atetrahydro-2H-phthalazin-1-one

: C₃₆H₄₈FN₃O₅

Guidance literature:: 2-{5-[3-(5-fluoro-2-methoxyphenyl)ethyl]tetrahydro-furan-2-yl}ethylamine; With caesium hydroxide monohydrate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h; Inert atmosphere;

2-(5-bromo-pentyl)-4-(3,4-dimethoxy-phenyl)-4a,5,8,8atetrahydro-2H-phthalazin-1-one; In N,N-dimethyl-formamide; at 20 ℃; for 18h; Inert atmosphere;
DOI:10.1021/jm8010993

Reference yield:

: 878661-48-4
2-{5-[3-(5-fluoro-2-methoxyphenyl)ethyl]tetrahydro-furan-2-yl}ethylamine

: 541-41-3
chloroformic acid ethyl ester

: 878663-10-6
2-{5-[3-(5-fluoro-2-methoxy-phenyl)-ethyl]-tetrahydro-furan-2-yl}-ethylamine-carbamic ethyl ester

Guidance literature:: With potassium carbonate; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2009.01.023 DOI:10.1021/jm8010993