1,1-Dimethylethyl N-[(1R)-1-phenyl-3-buten-1-yl]carbamate

Base Information

Chemical Name:1,1-Dimethylethyl N-[(1R)-1-phenyl-3-buten-1-yl]carbamate
CAS No.:439587-54-9
Molecular Formula:C₁₅H₂₁NO₂
Molecular Weight:247.337
Hs Code.:
DSSTox Substance ID:DTXSID201197426
Nikkaji Number:J2.176.274A

Synonyms:DTXSID201197426;439587-54-9;AKOS015966967;1,1-Dimethylethyl N-[(1R)-1-phenyl-3-buten-1-yl]carbamate

Suppliers and Price of 1,1-Dimethylethyl N-[(1R)-1-phenyl-3-buten-1-yl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,1-Dimethylethyl N-[(1R)-1-phenyl-3-buten-1-yl]carbamate

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:247.157228913
Heavy Atom Count:18
Complexity:275

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC=C)C1=CC=CC=C1
Isomeric SMILES:CC(C)(C)OC(=O)N[C@H](CC=C)C1=CC=CC=C1

Technology Process of 1,1-Dimethylethyl N-[(1R)-1-phenyl-3-buten-1-yl]carbamate

There total 5 articles about 1,1-Dimethylethyl N-[(1R)-1-phenyl-3-buten-1-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N-(t-butoxycarbonyl)-N-(4-methoxyphenyl)-benzylamine

: 439587-54-9
N-tert-butoxycarbonyl-(R)-1-phenylbut-3-enamine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi, (-)-sparteine / 1.) toluene, -78 deg C, 10 h, 2.) toluene

2: ceric ammonium nitrate

With n-butyllithium; ammonium cerium(IV) nitrate; (-)-sparteine;
DOI:10.1021/ja9538804

Reference yield:

: (4-Methoxy-phenyl)-((S)-1-phenyl-but-3-enyl)-carbamic acid tert-butyl ester

: 135865-77-9
(S)-N-(tert-Butoxycarbonyl)-1-phenyl-3-butenylamine

: 439587-54-9
N-tert-butoxycarbonyl-(R)-1-phenylbut-3-enamine

Guidance literature:: With ammonium cerium(IV) nitrate; Yield given. Title compound not separated from byproducts;
DOI:10.1021/ja9538804

Reference yield:

: 100-52-7
benzaldehyde

: 439587-54-9
N-tert-butoxycarbonyl-(R)-1-phenylbut-3-enamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: MgSO₄ / CH₂Cl₂

2.1: 92 percent / indium / methanol / 20 °C

3.1: lead tetraacetate / methanol; CH₂Cl₂ / 0.5 h

3.2: hydroxylamine hydrochloride / CH₂Cl₂; methanol / 0.5 h

3.3: triethylamine / CH₂Cl₂ / 2 h

With lead(IV) acetate; indium; magnesium sulfate; In methanol; dichloromethane; 2.1: Barbier allylation;
DOI:10.1021/jo0477244