tert-butyl 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-2-fluoro-5-iodobenzoate

Base Information

Chemical Name:tert-butyl 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-2-fluoro-5-iodobenzoate
CAS No.:1445862-90-7
Molecular Formula:C₁₈H₁₄ClF₄IO₄
Molecular Weight:532.658
Hs Code.:

Synonyms:tert-butyl 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-2-fluoro-5-iodobenzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-2-fluoro-5-iodobenzoate

Chemical Property:

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Technology Process of tert-butyl 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-2-fluoro-5-iodobenzoate

There total 2 articles about tert-butyl 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-2-fluoro-5-iodobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1000339-94-5
3-chloro-4-(trifluoromethoxy)phenol

: 1445862-86-1
tert-butyl 2,4-diflouro-5-iodobenzoate

: 1445862-90-7
tert-butyl 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-2-fluoro-5-iodobenzoate

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; at 20 ℃; for 48h;

Reference yield:

: 161531-51-7
2,4-difluoro-5-iodobenzoic acid

: 1445862-90-7
tert-butyl 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-2-fluoro-5-iodobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / tert-butyl alcohol / 40 °C

2: potassium carbonate / dimethyl sulfoxide / 48 h / 20 °C

With dmap; potassium carbonate; In dimethyl sulfoxide; tert-butyl alcohol;