1445862-86-1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 161531-51-7 2,4-difluoro-5-iodobenzoic acid 
• 75-65-0 tert-butyl alcohol 
• 1583-58-0 2,4-difluoro-benzoic acid 

Downstream Products

• 1445862-90-7 tert-butyl 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-2-fluoro-5-iodobenzoate 
• 1445862-87-2 tert-butyl 4-(4-chlorophenoxy)-2-fluoro-5-iodobenzoate 
• 1445862-62-3 4-(4-chlorophenoxy)-2-fluoro-N-(methylsulfonyl)-5-(2-propoxypyridin-3-yl)benzamide 
• 1445862-63-4 4-[3-chloro-4-(trifluoromethoxy)phenoxy]-5-(2-ethoxypyridin-3-yl)-2-fluoro-N-(methylsulfonyl)benzamide 
• 1445862-89-4 4-(4-chlorophenoxy)-2-fluoro-5-iodo-N-(methylsulfonyl)benzamide 
• 1445862-92-9 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-2-fluoro-5-iodo-N-(methylsulfonyl)benzamide 
• 1445862-88-3 4-(4-chlorophenoxy)-2-fluoro-5-iodobenzoic acid 
• 1445862-91-8 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-2-fluoro-5-iodobenzoic acid 

Relevant academic research and scientific papers

Cycloalkyl-substituted mesyl benzamide derivatives, and preparation method and medical application thereof

The invention relates to cycloalkyl-substitutedmesyl benzamide derivatives, and a preparation method and medical application thereof. The invention particularly discloses compounds disclosed as Formula (I) or pharmaceutically acceptable salts, stereoisomers, solvated compounds or prodrugs thereof, and a preparation method and application thereof. All the groups in the formula are defined in the specification.

N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF

The invention provides novel compounds having the general formula: [insert formula (I)] and pharmaceutically acceptable salts thereof, wherein the variables RA, subscript n, ring A, X2, L, subscript m, X1, ring D, R1, and RN have the meaning as described

SULFONAMIDE DERIVATIVES AND USE THEREOF AS VGSC INHIBITORS

The invention relates to new sulfonamide Nav1.7 inhibitors and pharmaceutically acceptable salts thereof, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. Nav1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain.