Technology Process of C23H18F3N3O2
There total 6 articles about C23H18F3N3O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-methylphenylacetaldehyde; C13H10F3N3O2;
With
sodium tris(acetoxy)borohydride; acetic acid;
In
tetrahydrofuran; dichloromethane;
at 20 ℃;
for 2h;
trimethyl orthoformate;
With
trifluoroacetic acid;
at 20 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / dimethyl sulfoxide / 100 °C
2.1: ammonia / methanol / 24 h / 100 °C / Sealed tube
3.1: hydrogen / Raney nickel / methanol / 24 h / 20 °C / 775.74 - 1034.32 Torr
4.1: sodium tris(acetoxy)borohydride; acetic acid / tetrahydrofuran; dichloromethane / 2 h / 20 °C
4.2: 2 h / 20 °C
With
ammonia; hydrogen; sodium tris(acetoxy)borohydride; potassium carbonate; acetic acid;
Raney nickel;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ammonia / methanol / 24 h / 100 °C / Sealed tube
2.1: hydrogen / Raney nickel / methanol / 24 h / 20 °C / 775.74 - 1034.32 Torr
3.1: sodium tris(acetoxy)borohydride; acetic acid / tetrahydrofuran; dichloromethane / 2 h / 20 °C
3.2: 2 h / 20 °C
With
ammonia; hydrogen; sodium tris(acetoxy)borohydride; acetic acid;
Raney nickel;
In
tetrahydrofuran; methanol; dichloromethane;