Fosbretabulin tromethamine

Base Information

Chemical Name:Fosbretabulin tromethamine
CAS No.:404886-32-4
Molecular Formula:C₄H₁₁NO₃*C₁₈H₂₁O₈P
Molecular Weight:517.47
Hs Code.:
UNII:GBW044919E
Wikidata:Q27279017
NCI Thesaurus Code:C83721
ChEMBL ID:CHEMBL2105643

Synonyms:Fosbretabulin tromethamine;Zybrestat;404886-32-4;Fosbretabulin tromethamine [USAN];UNII-GBW044919E;GBW044919E;Fosbretabulin tromethamine (USAN);2-amino-2-(hydroxymethyl)propane-1,3-diol;[2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate;CHEMBL2105643;FOSBRETABULIN TROMETHAMINE [MI];FOSBRETABULIN TROMETHAMINE [WHO-DD];D09619;Q27279017;1,3-Dihydroxy-2-(hydroxymethyl)propan-2-aminium 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl hydrogen phosphate

Suppliers and Price of Fosbretabulin tromethamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
FOSBRETABULIN TROMETHAMINE 95.00%
5MG
$ 504.94

Total 0 raw suppliers

Chemical Property of Fosbretabulin tromethamine

Chemical Property:

Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:11
Exact Mass:517.17129783
Heavy Atom Count:35
Complexity:562

Purity/Quality:: FOSBRETABULIN TROMETHAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C=CC2=CC(=C(C(=C2)OC)OC)OC)OP(=O)(O)O.C(C(CO)(CO)N)O
Isomeric SMILES:COC1=C(C=C(C=C1)/C=C\C2=CC(=C(C(=C2)OC)OC)OC)OP(=O)(O)O.C(C(CO)(CO)N)O
Recent ClinicalTrials:Bevacizumab With or Without Fosbretabulin Tromethamine in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer
Recent EU Clinical Trials:FOCUS: A Multicenter, Multinational, Double-blind, 2-Arm, Randomized, Phase 2/3, Study of Physician’s Choice Chemotherapy (PCC) (Weekly Paclitaxel or Pegylated Liposomal Doxorubicin [PLD]) Plus Bevacizumab and CA4P Versus PCC Plus Bevacizumab and Placebo for Subjects with Platinum-Resistant, Recurrent, Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancer

Technology Process of Fosbretabulin tromethamine

There total 1 articles about Fosbretabulin tromethamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%