bis(1,1-dimethylethyl)[[3-phenyl-1-[3-(phenylseleno)propyl]-2-propynyl]oxy]silane

Base Information

• Chemical Name: bis(1,1-dimethylethyl)[[3-phenyl-1-[3-(phenylseleno)propyl]-2-propynyl]oxy]silane
• CAS No.: 163772-69-8
• Molecular Formula: C₂₆H₃₆OSeSi
• Molecular Weight: 471.617
• Mol file: 163772-69-8.mol

Synonyms:bis(1,1-dimethylethyl)[[3-phenyl-1-[3-(phenylseleno)propyl]-2-propynyl]oxy]silane

Chemical Property of bis(1,1-dimethylethyl)[[3-phenyl-1-[3-(phenylseleno)propyl]-2-propynyl]oxy]silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis(1,1-dimethylethyl)[[3-phenyl-1-[3-(phenylseleno)propyl]-2-propynyl]oxy]silane

There total 4 articles about bis(1,1-dimethylethyl)[[3-phenyl-1-[3-(phenylseleno)propyl]-2-propynyl]oxy]silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

di-tert-butylchlorosilane (56310-18-0) + 1-phenyl-6-(phenylseleno)-1-hexyn-3-ol (163772-68-7) → bis(1,1-dimethylethyl)[[3-phenyl-1-[3-(phenylseleno)propyl]-2-propynyl]oxy]silane (163772-69-8)

Guidance literature:

With 1H-imidazole; In tetrahydrofuran; Heating;

DOI:10.1039/c39950000319

Reference yield:

4-(Phenylseleno)butanal (124854-74-6) → bis(1,1-dimethylethyl)[[3-phenyl-1-[3-(phenylseleno)propyl]-2-propynyl]oxy]silane (163772-69-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 0.25 h / -78 °C

1.2: 71 percent / tetrahydrofuran; hexane / 0.75 h / -78 °C

2.1: 91 percent / imidazole / tetrahydrofuran / 2.5 h / Heating

With 1H-imidazole; n-butyllithium; In tetrahydrofuran; hexane;

DOI:10.1021/jo001124x

Reference yield:

phenylacetylene (536-74-3) → bis(1,1-dimethylethyl)[[3-phenyl-1-[3-(phenylseleno)propyl]-2-propynyl]oxy]silane (163772-69-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 0.25 h / -78 °C

1.2: 71 percent / tetrahydrofuran; hexane / 0.75 h / -78 °C

2.1: 91 percent / imidazole / tetrahydrofuran / 2.5 h / Heating

With 1H-imidazole; n-butyllithium; In tetrahydrofuran; hexane;

DOI:10.1021/jo001124x

upstream raw materials:

di-tert-butylchlorosilane

1-phenyl-6-(phenylseleno)-1-hexyn-3-ol

4-(Phenylseleno)butanal

phenylacetylene